About 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine
4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine (PubChem CID 58221346) has the molecular formula C15H14BrFN4O2
and a molecular weight of 381.21 g/mol. Its IUPAC name is 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine.
Molecular Properties
| Compound Name | 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine |
| PubChem CID | 58221346 |
| Molecular Formula | C15H14BrFN4O2 |
| Molecular Weight | 381.21 g/mol |
| Exact Mass | 380.03 |
| IUPAC Name | 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine |
| SMILES | COCCOc1cnc(N)nc1-c1c[nH]c2c(F)cc(Br)cc12 |
| InChI | InChI=1S/C15H14BrFN4O2/c1-22-2-3-23-12-7-20-15(18)21-14(12)10-6-19-13-9(10)4-8(16)5-11(13)17/h4-7,19H,2-3H2,1H3,(H2,18,20,21) |
| InChIKey | NDDQKTJMPMALIB-UHFFFAOYSA-N |
| XLogP | 3.13 |
| TPSA | 86.05 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 23 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 381.21 |
| LogP ≤ 5 | 3.13 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine?
The IUPAC name of 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine (CID 58221346) is 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine.
What is the SMILES notation for 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine?
The canonical SMILES for 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine is COCCOc1cnc(N)nc1-c1c[nH]c2c(F)cc(Br)cc12.
What is the InChIKey of 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine?
The InChIKey is NDDQKTJMPMALIB-UHFFFAOYSA-N. The full InChI is InChI=1S/C15H14BrFN4O2/c1-22-2-3-23-12-7-20-15(18)21-14(12)10-6-19-13-9(10)4-8(16)5-11(13)17/h4-7,19H,2-3H2,1H3,(H2,18,20,21).
What are the key properties of 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine?
4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine has a molecular weight of 381.21 g/mol, XLogP of 3.13, 5 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(5-bromo-7-fluoro-1H-indol-3-yl)-5-(2-methoxyethoxy)pyrimidin-2-amine is sourced from PubChem (CID 58221346), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).