About 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one
6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one (PubChem CID 58227965) has the molecular formula C23H23ClF2N4O2
and a molecular weight of 460.91 g/mol. Its IUPAC name is 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one.
Molecular Properties
| Compound Name | 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one |
| PubChem CID | 58227965 |
| Molecular Formula | C23H23ClF2N4O2 |
| Molecular Weight | 460.91 g/mol |
| Exact Mass | 460.15 |
| IUPAC Name | 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one |
| SMILES | Cc1ncc(C(CCC(=O)c2c(Cl)ccc3[nH]c(=O)ccc23)N2CCC(F)(F)CC2)cn1 |
| InChI | InChI=1S/C23H23ClF2N4O2/c1-14-27-12-15(13-28-14)19(30-10-8-23(25,26)9-11-30)5-6-20(31)22-16-2-7-21(32)29-18(16)4-3-17(22)24/h2-4,7,12-13,19H,5-6,8-11H2,1H3,(H,29,32) |
| InChIKey | FORCMPDNRZJGHR-UHFFFAOYSA-N |
| XLogP | 4.72 |
| TPSA | 78.95 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 460.91 |
| LogP ≤ 5 | 4.72 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one?
The IUPAC name of 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one (CID 58227965) is 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one.
What is the SMILES notation for 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one?
The canonical SMILES for 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one is Cc1ncc(C(CCC(=O)c2c(Cl)ccc3[nH]c(=O)ccc23)N2CCC(F)(F)CC2)cn1.
What is the InChIKey of 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one?
The InChIKey is FORCMPDNRZJGHR-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H23ClF2N4O2/c1-14-27-12-15(13-28-14)19(30-10-8-23(25,26)9-11-30)5-6-20(31)22-16-2-7-21(32)29-18(16)4-3-17(22)24/h2-4,7,12-13,19H,5-6,8-11H2,1H3,(H,29,32).
What are the key properties of 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one?
6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one has a molecular weight of 460.91 g/mol, XLogP of 4.72, 6 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 6-chloro-5-[4-(4,4-difluoropiperidin-1-yl)-4-(2-methylpyrimidin-5-yl)butanoyl]-1H-quinolin-2-one is sourced from PubChem (CID 58227965), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).