About N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide
N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide (PubChem CID 59174354) has the molecular formula C28H30FN5O4
and a molecular weight of 519.58 g/mol. Its IUPAC name is N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide.
Molecular Properties
| Compound Name | N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide |
| PubChem CID | 59174354 |
| Molecular Formula | C28H30FN5O4 |
| Molecular Weight | 519.58 g/mol |
| Exact Mass | 519.23 |
| IUPAC Name | N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide |
| SMILES | C=CC(=O)N(C)Cc1ccc(Oc2nc(Nc3cccc(OCCCN4CCCC4=O)c3)ncc2F)cc1 |
| InChI | InChI=1S/C28H30FN5O4/c1-3-25(35)33(2)19-20-10-12-22(13-11-20)38-27-24(29)18-30-28(32-27)31-21-7-4-8-23(17-21)37-16-6-15-34-14-5-9-26(34)36/h3-4,7-8,10-13,17-18H,1,5-6,9,14-16,19H2,2H3,(H,30,31,32) |
| InChIKey | YMQJXVSXBRCXQT-UHFFFAOYSA-N |
| XLogP | 4.69 |
| TPSA | 96.89 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 12 |
| Heavy Atoms | 38 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 519.58 |
| LogP ≤ 5 | 4.69 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 7 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide?
The IUPAC name of N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide (CID 59174354) is N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide.
What is the SMILES notation for N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide?
The canonical SMILES for N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide is C=CC(=O)N(C)Cc1ccc(Oc2nc(Nc3cccc(OCCCN4CCCC4=O)c3)ncc2F)cc1.
What is the InChIKey of N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide?
The InChIKey is YMQJXVSXBRCXQT-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H30FN5O4/c1-3-25(35)33(2)19-20-10-12-22(13-11-20)38-27-24(29)18-30-28(32-27)31-21-7-4-8-23(17-21)37-16-6-15-34-14-5-9-26(34)36/h3-4,7-8,10-13,17-18H,1,5-6,9,14-16,19H2,2H3,(H,30,31,32).
What are the key properties of N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide?
N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide has a molecular weight of 519.58 g/mol, XLogP of 4.69, 12 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for N-[[4-[5-fluoro-2-[3-[3-(2-oxopyrrolidin-1-yl)propoxy]anilino]pyrimidin-4-yl]oxyphenyl]methyl]-N-methylprop-2-enamide is sourced from PubChem (CID 59174354), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).