(2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide

C17H20N6O2S — CID 59293765

IUPAC(2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
SMILESCc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1cncc(C2CC2)n1
InChIInChI=1S/C17H20N6O2S/c1-9-14(12-8-19-7-11(21-12)10-4-5-10)26-16(20-9)22-17(25)23-6-2-3-13(23)15(18)24/h7-8,10,13H,2-6H2,1H3,(H2,18,24)(H,20,22,25)/t13-/m0/s1
InChIKeyUFHICFIZBMFSOO-ZDUSSCGKSA-N
MW372.45 g/mol
LogP2.27
Rot. Bonds4

About (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide

(2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide (PubChem CID 59293765) has the molecular formula C17H20N6O2S and a molecular weight of 372.45 g/mol. Its IUPAC name is (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide.

Molecular Properties

Compound Name(2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
PubChem CID59293765
Molecular FormulaC17H20N6O2S
Molecular Weight372.45 g/mol
Exact Mass372.14
IUPAC Name(2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
SMILESCc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1cncc(C2CC2)n1
InChIInChI=1S/C17H20N6O2S/c1-9-14(12-8-19-7-11(21-12)10-4-5-10)26-16(20-9)22-17(25)23-6-2-3-13(23)15(18)24/h7-8,10,13H,2-6H2,1H3,(H2,18,24)(H,20,22,25)/t13-/m0/s1
InChIKeyUFHICFIZBMFSOO-ZDUSSCGKSA-N
XLogP2.27
TPSA114.10 Ų
H-Bond Donors2
H-Bond Acceptors6
Rotatable Bonds4
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500372.45
LogP ≤ 52.27
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 106

Analyze (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

(2S)-1-N-[5-[2-(diethylamino)pyrimidin-4-yl]-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
CID 59293740
tert-butyl N-[4-[2-[[(2S)-2-carbamoylpyrrolidine-1-carbonyl]amino]-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-2-yl]carbamate
CID 87536482
(2S)-1-N-[5-[2-[1,1,1,3,3,3-hexadeuterio-2-(trideuteriomethyl)propan-2-yl]pyrimidin-4-yl]-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
CID 59293648
(2S)-1-N-[5-[2-(1-hydroxy-2-methylpropan-2-yl)pyrimidin-4-yl]-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
CID 134149428
(2S)-1-N-[4-methyl-5-[3-methyl-1-oxo-3-(trifluoromethyl)-2H-isoindol-5-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
CID 167432467
1-N-[4-methyl-5-[2-(1,1,1,2-tetrafluoropropan-2-yl)-4-pyridinyl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
CID 146697209
(2S)-1-N-[4-methyl-5-[1-(1,1,1-trifluoro-2-methylpropan-2-yl)-2H-pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
CID 166064120
1-N-[4-methyl-5-[(4S)-1-oxo-4-(trifluoromethyl)-3,4-dihydro-2H-isoquinolin-6-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
CID 175483185
N-[5-(2-cyclobutyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]-2-(2-phenylacetyl)pyrrolidine-1-carboxamide
CID 143824341
(2S)-1-N-[5-[2-[2-[4-[3-(dimethylamino)propoxy]phenyl]propan-2-yl]-4-pyridinyl]-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
CID 59293680
2-carbamothioyl-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)-4-pyridinyl]-1,3-thiazol-2-yl]pyrrolidine-1-carboxamide
CID 171535071
(2S,4R)-1-N-[5-(2-tert-butylpyrimidin-4-yl)-4-methyl-1,3-thiazol-2-yl]-4-hydroxypyrrolidine-1,2-dicarboxamide
CID 42646248

Frequently Asked Questions

What is the IUPAC name of (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide?
The IUPAC name of (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide (CID 59293765) is (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide.
What is the SMILES notation for (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide?
The canonical SMILES for (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide is Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1cncc(C2CC2)n1.
What is the InChIKey of (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide?
The InChIKey is UFHICFIZBMFSOO-ZDUSSCGKSA-N. The full InChI is InChI=1S/C17H20N6O2S/c1-9-14(12-8-19-7-11(21-12)10-4-5-10)26-16(20-9)22-17(25)23-6-2-3-13(23)15(18)24/h7-8,10,13H,2-6H2,1H3,(H2,18,24)(H,20,22,25)/t13-/m0/s1.
What are the key properties of (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide?
(2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide has a molecular weight of 372.45 g/mol, XLogP of 2.27, 4 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for (2S)-1-N-[5-(6-cyclopropylpyrazin-2-yl)-4-methyl-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide is sourced from PubChem (CID 59293765), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).