N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine

C18H14F2N6 — CID 59298863

IUPACN-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine
SMILESFc1cc(F)cc(-c2cc3nccn3c(Nc3cc(C4CC4)[nH]n3)n2)c1
InChIInChI=1S/C18H14F2N6/c19-12-5-11(6-13(20)7-12)14-9-17-21-3-4-26(17)18(22-14)23-16-8-15(24-25-16)10-1-2-10/h3-10H,1-2H2,(H2,22,23,24,25)
InChIKeyFPSOEHRNOLJWRI-UHFFFAOYSA-N
MW352.35 g/mol
LogP4.02
Rot. Bonds4

About N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine

N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine (PubChem CID 59298863) has the molecular formula C18H14F2N6 and a molecular weight of 352.35 g/mol. Its IUPAC name is N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine.

Molecular Properties

Compound NameN-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine
PubChem CID59298863
Molecular FormulaC18H14F2N6
Molecular Weight352.35 g/mol
Exact Mass352.12
IUPAC NameN-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine
SMILESFc1cc(F)cc(-c2cc3nccn3c(Nc3cc(C4CC4)[nH]n3)n2)c1
InChIInChI=1S/C18H14F2N6/c19-12-5-11(6-13(20)7-12)14-9-17-21-3-4-26(17)18(22-14)23-16-8-15(24-25-16)10-1-2-10/h3-10H,1-2H2,(H2,22,23,24,25)
InChIKeyFPSOEHRNOLJWRI-UHFFFAOYSA-N
XLogP4.02
TPSA70.90 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds4
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500352.35
LogP ≤ 54.02
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

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Related Compounds

N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(1H-indol-5-yl)imidazo[1,2-c]pyrimidin-5-amine
CID 59299033
N-[4-[5-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]imidazo[1,2-c]pyrimidin-7-yl]phenyl]acetamide
CID 59298957
[(1R,2R,3R)-3-[3-[[7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-1H-pyrazol-5-yl]-2-fluorocyclopentyl] N-(1-methylcyclopropyl)carbamate
CID 170118895
N-[[3-[5-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]imidazo[1,2-c]pyrimidin-7-yl]phenyl]methyl]cyclopropanecarboxamide
CID 46893844
3-[5-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]imidazo[1,2-c]pyrimidin-7-yl]cyclohepta-1,3,5-triene-1-carbaldehyde
CID 143218655
[3-[3-[(7-pyrimidin-5-ylimidazo[1,2-c]pyrimidin-5-yl)amino]-1H-pyrazol-5-yl]cyclopentyl] N-(1-bicyclo[1.1.1]pentanyl)carbamate
CID 169142780
[(1S,2R,4R)-4-[3-[[7-(3-chloro-4-fluorophenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-1H-pyrazol-5-yl]-2-fluorocyclopentyl] N-(1-bicyclo[1.1.1]pentanyl)carbamate
CID 169142138
[4-[5-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]imidazo[1,2-c]pyrimidin-7-yl]sulfanylphenyl]-piperazin-1-ylmethanone
CID 59299073
[(1S,2R,3S)-3-[3-[[7-(3-chloro-4-fluorophenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]-1H-pyrazol-5-yl]-2-fluorocyclopentyl] N-propan-2-ylcarbamate
CID 169141116
4-[5-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]imidazo[1,2-c]pyrimidin-7-yl]sulfanyl-N-piperidin-3-ylbenzamide
CID 59299114
[(1S,2R,3S)-2-fluoro-3-[3-[[7-(1-methylpyrazol-4-yl)imidazo[1,2-c]pyrimidin-5-yl]amino]-1H-pyrazol-5-yl]cyclopentyl] N-(1-methylcyclopropyl)carbamate
CID 169142559
N-(3,5-difluorophenyl)-7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-amine
CID 20806138

Frequently Asked Questions

What is the IUPAC name of N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine?
The IUPAC name of N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine (CID 59298863) is N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine.
What is the SMILES notation for N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine?
The canonical SMILES for N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine is Fc1cc(F)cc(-c2cc3nccn3c(Nc3cc(C4CC4)[nH]n3)n2)c1.
What is the InChIKey of N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine?
The InChIKey is FPSOEHRNOLJWRI-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H14F2N6/c19-12-5-11(6-13(20)7-12)14-9-17-21-3-4-26(17)18(22-14)23-16-8-15(24-25-16)10-1-2-10/h3-10H,1-2H2,(H2,22,23,24,25).
What are the key properties of N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine?
N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine has a molecular weight of 352.35 g/mol, XLogP of 4.02, 4 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-(5-cyclopropyl-1H-pyrazol-3-yl)-7-(3,5-difluorophenyl)imidazo[1,2-c]pyrimidin-5-amine is sourced from PubChem (CID 59298863), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).