About N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide
N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide (PubChem CID 59463416) has the molecular formula C25H20N4O4S2
and a molecular weight of 504.59 g/mol. Its IUPAC name is N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide.
Molecular Properties
| Compound Name | N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide |
| PubChem CID | 59463416 |
| Molecular Formula | C25H20N4O4S2 |
| Molecular Weight | 504.59 g/mol |
| Exact Mass | 504.09 |
| IUPAC Name | N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide |
| SMILES | O=C(Nc1cscc1S(=O)(=O)c1ccccc1)N1N=C(c2cccnc2)CC1c1ccccc1O |
| InChI | InChI=1S/C25H20N4O4S2/c30-23-11-5-4-10-19(23)22-13-20(17-7-6-12-26-14-17)28-29(22)25(31)27-21-15-34-16-24(21)35(32,33)18-8-2-1-3-9-18/h1-12,14-16,22,30H,13H2,(H,27,31) |
| InChIKey | BULDOYTUTLNLON-UHFFFAOYSA-N |
| XLogP | 5.06 |
| TPSA | 111.96 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 35 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 504.59 |
| LogP ≤ 5 | 5.06 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'mannich_A(296)', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide?
The IUPAC name of N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide (CID 59463416) is N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide.
What is the SMILES notation for N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide?
The canonical SMILES for N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide is O=C(Nc1cscc1S(=O)(=O)c1ccccc1)N1N=C(c2cccnc2)CC1c1ccccc1O.
What is the InChIKey of N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide?
The InChIKey is BULDOYTUTLNLON-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H20N4O4S2/c30-23-11-5-4-10-19(23)22-13-20(17-7-6-12-26-14-17)28-29(22)25(31)27-21-15-34-16-24(21)35(32,33)18-8-2-1-3-9-18/h1-12,14-16,22,30H,13H2,(H,27,31).
What are the key properties of N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide?
N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide has a molecular weight of 504.59 g/mol, XLogP of 5.06, 5 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(benzenesulfonyl)thiophen-3-yl]-3-(2-hydroxyphenyl)-5-pyridin-3-yl-3,4-dihydropyrazole-2-carboxamide is sourced from PubChem (CID 59463416), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).