About 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone
1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone (PubChem CID 59647140) has the molecular formula C18H21N5O3S
and a molecular weight of 387.47 g/mol. Its IUPAC name is 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone.
Molecular Properties
| Compound Name | 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone |
| PubChem CID | 59647140 |
| Molecular Formula | C18H21N5O3S |
| Molecular Weight | 387.47 g/mol |
| Exact Mass | 387.14 |
| IUPAC Name | 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone |
| SMILES | COc1ccnc(-c2nc(NC(C)(C)CO)nc3sc(C(C)=O)c(N)c23)c1 |
| InChI | InChI=1S/C18H21N5O3S/c1-9(25)15-13(19)12-14(11-7-10(26-4)5-6-20-11)21-17(22-16(12)27-15)23-18(2,3)8-24/h5-7,24H,8,19H2,1-4H3,(H,21,22,23) |
| InChIKey | HHWCMZXBMMTJED-UHFFFAOYSA-N |
| XLogP | 2.73 |
| TPSA | 123.25 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 27 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 387.47 |
| LogP ≤ 5 | 2.73 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 9 |
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Frequently Asked Questions
What is the IUPAC name of 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone?
The IUPAC name of 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone (CID 59647140) is 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone.
What is the SMILES notation for 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone?
The canonical SMILES for 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone is COc1ccnc(-c2nc(NC(C)(C)CO)nc3sc(C(C)=O)c(N)c23)c1.
What is the InChIKey of 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone?
The InChIKey is HHWCMZXBMMTJED-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H21N5O3S/c1-9(25)15-13(19)12-14(11-7-10(26-4)5-6-20-11)21-17(22-16(12)27-15)23-18(2,3)8-24/h5-7,24H,8,19H2,1-4H3,(H,21,22,23).
What are the key properties of 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone?
1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone has a molecular weight of 387.47 g/mol, XLogP of 2.73, 6 rotatable bonds, 3 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[5-amino-2-[(1-hydroxy-2-methylpropan-2-yl)amino]-4-(4-methoxy-2-pyridinyl)thieno[2,3-d]pyrimidin-6-yl]ethanone is sourced from PubChem (CID 59647140), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).