About 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone
1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone (PubChem CID 59845682) has the molecular formula C28H31F3N6O4
and a molecular weight of 572.59 g/mol. Its IUPAC name is 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone.
Molecular Properties
| Compound Name | 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone |
| PubChem CID | 59845682 |
| Molecular Formula | C28H31F3N6O4 |
| Molecular Weight | 572.59 g/mol |
| Exact Mass | 572.24 |
| IUPAC Name | 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone |
| SMILES | CC(=O)c1cccc(CNC2CCC(CNc3nc(NCc4ccccc4OC(F)(F)F)ncc3[N+](=O)[O-])CC2)c1 |
| InChI | InChI=1S/C28H31F3N6O4/c1-18(38)21-7-4-5-20(13-21)15-32-23-11-9-19(10-12-23)14-33-26-24(37(39)40)17-35-27(36-26)34-16-22-6-2-3-8-25(22)41-28(29,30)31/h2-8,13,17,19,23,32H,9-12,14-16H2,1H3,(H2,33,34,35,36) |
| InChIKey | RBOTVWSEDIFPGH-UHFFFAOYSA-N |
| XLogP | 5.86 |
| TPSA | 131.31 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 12 |
| Heavy Atoms | 41 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 572.59 |
| LogP ≤ 5 | 5.86 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 9 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'nitro_group', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone?
The IUPAC name of 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone (CID 59845682) is 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone.
What is the SMILES notation for 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone?
The canonical SMILES for 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone is CC(=O)c1cccc(CNC2CCC(CNc3nc(NCc4ccccc4OC(F)(F)F)ncc3[N+](=O)[O-])CC2)c1.
What is the InChIKey of 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone?
The InChIKey is RBOTVWSEDIFPGH-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H31F3N6O4/c1-18(38)21-7-4-5-20(13-21)15-32-23-11-9-19(10-12-23)14-33-26-24(37(39)40)17-35-27(36-26)34-16-22-6-2-3-8-25(22)41-28(29,30)31/h2-8,13,17,19,23,32H,9-12,14-16H2,1H3,(H2,33,34,35,36).
What are the key properties of 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone?
1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone has a molecular weight of 572.59 g/mol, XLogP of 5.86, 12 rotatable bonds, 3 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[3-[[[4-[[[5-nitro-2-[[2-(trifluoromethoxy)phenyl]methylamino]pyrimidin-4-yl]amino]methyl]cyclohexyl]amino]methyl]phenyl]ethanone is sourced from PubChem (CID 59845682), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).