About cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate
cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate (PubChem CID 6235030) has the molecular formula C22H26FN3O4S
and a molecular weight of 447.53 g/mol. Its IUPAC name is cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate.
Molecular Properties
| Compound Name | cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate |
| PubChem CID | 6235030 |
| Molecular Formula | C22H26FN3O4S |
| Molecular Weight | 447.53 g/mol |
| Exact Mass | 447.16 |
| IUPAC Name | cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate |
| SMILES | O=C(/C=C/c1ccc(F)cc1)NC(=S)N1CCNC(=O)C1CC(=O)OC1CCCCC1 |
| InChI | InChI=1S/C22H26FN3O4S/c23-16-9-6-15(7-10-16)8-11-19(27)25-22(31)26-13-12-24-21(29)18(26)14-20(28)30-17-4-2-1-3-5-17/h6-11,17-18H,1-5,12-14H2,(H,24,29)(H,25,27,31)/b11-8+ |
| InChIKey | MAAQCFJUUKHIOM-DHZHZOJOSA-N |
| XLogP | 2.31 |
| TPSA | 87.74 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 447.53 |
| LogP ≤ 5 | 2.31 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}, {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate?
The IUPAC name of cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate (CID 6235030) is cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate.
What is the SMILES notation for cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate?
The canonical SMILES for cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate is O=C(/C=C/c1ccc(F)cc1)NC(=S)N1CCNC(=O)C1CC(=O)OC1CCCCC1.
What is the InChIKey of cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate?
The InChIKey is MAAQCFJUUKHIOM-DHZHZOJOSA-N. The full InChI is InChI=1S/C22H26FN3O4S/c23-16-9-6-15(7-10-16)8-11-19(27)25-22(31)26-13-12-24-21(29)18(26)14-20(28)30-17-4-2-1-3-5-17/h6-11,17-18H,1-5,12-14H2,(H,24,29)(H,25,27,31)/b11-8+.
What are the key properties of cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate?
cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate has a molecular weight of 447.53 g/mol, XLogP of 2.31, 5 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for cyclohexyl 2-[1-[[(E)-3-(4-fluorophenyl)prop-2-enoyl]carbamothioyl]-3-oxopiperazin-2-yl]acetate is sourced from PubChem (CID 6235030), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).