About 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine
1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine (PubChem CID 63316318) has the molecular formula C11H18F3N5
and a molecular weight of 277.29 g/mol. Its IUPAC name is 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine.
Molecular Properties
| Compound Name | 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine |
| PubChem CID | 63316318 |
| Molecular Formula | C11H18F3N5 |
| Molecular Weight | 277.29 g/mol |
| Exact Mass | 277.15 |
| IUPAC Name | 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine |
| SMILES | Nc1ccn(CCN2CCN(CC(F)(F)F)CC2)n1 |
| InChI | InChI=1S/C11H18F3N5/c12-11(13,14)9-18-5-3-17(4-6-18)7-8-19-2-1-10(15)16-19/h1-2H,3-9H2,(H2,15,16) |
| InChIKey | QHRYKHZJMGCEPO-UHFFFAOYSA-N |
| XLogP | 0.65 |
| TPSA | 50.32 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 19 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 277.29 |
| LogP ≤ 5 | 0.65 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine?
The IUPAC name of 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine (CID 63316318) is 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine.
What is the SMILES notation for 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine?
The canonical SMILES for 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine is Nc1ccn(CCN2CCN(CC(F)(F)F)CC2)n1.
What is the InChIKey of 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine?
The InChIKey is QHRYKHZJMGCEPO-UHFFFAOYSA-N. The full InChI is InChI=1S/C11H18F3N5/c12-11(13,14)9-18-5-3-17(4-6-18)7-8-19-2-1-10(15)16-19/h1-2H,3-9H2,(H2,15,16).
What are the key properties of 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine?
1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine has a molecular weight of 277.29 g/mol, XLogP of 0.65, 4 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[2-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]ethyl]pyrazol-3-amine is sourced from PubChem (CID 63316318), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).