N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide

C12H8F2N2O2 — CID 63864937

IUPACN-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide
SMILESO=C(Nc1ccc(F)c(F)c1)c1cncc(O)c1
InChIInChI=1S/C12H8F2N2O2/c13-10-2-1-8(4-11(10)14)16-12(18)7-3-9(17)6-15-5-7/h1-6,17H,(H,16,18)
InChIKeyCZXFMUPKCRKFIX-UHFFFAOYSA-N
MW250.20 g/mol
LogP2.32
Rot. Bonds2

About N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide

N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide (PubChem CID 63864937) has the molecular formula C12H8F2N2O2 and a molecular weight of 250.20 g/mol. Its IUPAC name is N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide.

Molecular Properties

Compound NameN-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide
PubChem CID63864937
Molecular FormulaC12H8F2N2O2
Molecular Weight250.20 g/mol
Exact Mass250.06
IUPAC NameN-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide
SMILESO=C(Nc1ccc(F)c(F)c1)c1cncc(O)c1
InChIInChI=1S/C12H8F2N2O2/c13-10-2-1-8(4-11(10)14)16-12(18)7-3-9(17)6-15-5-7/h1-6,17H,(H,16,18)
InChIKeyCZXFMUPKCRKFIX-UHFFFAOYSA-N
XLogP2.32
TPSA62.22 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds2
Heavy Atoms18
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500250.20
LogP ≤ 52.32
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

Analyze N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(4-chloro-3-fluorophenyl)-5-hydroxypyridine-3-carboxamide
CID 63864787
2-fluoro-4-[(5-hydroxypyridine-3-carbonyl)amino]benzoic acid
CID 107792618
5-(2,6-difluoroanilino)-N-(3,4-difluorophenyl)pyridine-3-carboxamide
CID 109246460
3-N-(3,4-difluorophenyl)-5-N-propan-2-ylpyridine-3,5-dicarboxamide
CID 109101520
5-hydroxy-N-(4-methylsulfanylphenyl)pyridine-3-carboxamide
CID 63864054
N-(3-chloro-4-methylphenyl)-5-hydroxypyridine-3-carboxamide
CID 63865104
N-(4-bromophenyl)-5-hydroxypyridine-3-carboxamide
CID 63851687
N-(4-aminophenyl)-5-hydroxypyridine-3-carboxamide
CID 63851550
N-(2,5-difluorophenyl)-5-hydroxypyridine-3-carboxamide
CID 63864589
4,5-difluoro-2-[(5-hydroxypyridine-3-carbonyl)amino]benzoic acid
CID 63851155
5-N-(3,4-difluorophenyl)-3-N-[(4-fluorophenyl)methyl]pyridine-3,5-dicarboxamide
CID 109105648
5-(4-acetylpiperazine-1-carbonyl)-N-(3,4-difluorophenyl)pyridine-3-carboxamide
CID 109104830

Frequently Asked Questions

What is the IUPAC name of N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide?
The IUPAC name of N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide (CID 63864937) is N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide.
What is the SMILES notation for N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide?
The canonical SMILES for N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide is O=C(Nc1ccc(F)c(F)c1)c1cncc(O)c1.
What is the InChIKey of N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide?
The InChIKey is CZXFMUPKCRKFIX-UHFFFAOYSA-N. The full InChI is InChI=1S/C12H8F2N2O2/c13-10-2-1-8(4-11(10)14)16-12(18)7-3-9(17)6-15-5-7/h1-6,17H,(H,16,18).
What are the key properties of N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide?
N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide has a molecular weight of 250.20 g/mol, XLogP of 2.32, 2 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for N-(3,4-difluorophenyl)-5-hydroxypyridine-3-carboxamide is sourced from PubChem (CID 63864937), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).