2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide

C20H22F2N2O2 — CID 646544

IUPAC2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide
SMILESO=C(CN1CCC(O)(c2ccc(F)cc2)CC1)NCc1ccc(F)cc1
InChIInChI=1S/C20H22F2N2O2/c21-17-5-1-15(2-6-17)13-23-19(25)14-24-11-9-20(26,10-12-24)16-3-7-18(22)8-4-16/h1-8,26H,9-14H2,(H,23,25)
InChIKeyIUGWRZPTBAZRQI-UHFFFAOYSA-N
MW360.40 g/mol
LogP2.56
Rot. Bonds5

About 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide

2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide (PubChem CID 646544) has the molecular formula C20H22F2N2O2 and a molecular weight of 360.40 g/mol. Its IUPAC name is 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide.

Molecular Properties

Compound Name2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide
PubChem CID646544
Molecular FormulaC20H22F2N2O2
Molecular Weight360.40 g/mol
Exact Mass360.16
IUPAC Name2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide
SMILESO=C(CN1CCC(O)(c2ccc(F)cc2)CC1)NCc1ccc(F)cc1
InChIInChI=1S/C20H22F2N2O2/c21-17-5-1-15(2-6-17)13-23-19(25)14-24-11-9-20(26,10-12-24)16-3-7-18(22)8-4-16/h1-8,26H,9-14H2,(H,23,25)
InChIKeyIUGWRZPTBAZRQI-UHFFFAOYSA-N
XLogP2.56
TPSA52.57 Ų
H-Bond Donors2
H-Bond Acceptors3
Rotatable Bonds5
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500360.40
LogP ≤ 52.56
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 103

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Related Compounds

SR1555
CID 71470549
N-[1-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-3-methyl-1-oxobutan-2-yl]benzamide
CID 57889234
[2-[4-[Hydroxy(diphenyl)methyl]piperidin-1-yl]-2-oxoethyl]urea
CID 2541146
N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidine-1-carboxamide
CID 162370301
2-[4-(4-Fluoro-phenyl)-4-hydroxy-piperidin-1-yl]-N-(2-methyl-cyclohexyl)-acetamide
CID 650020
N-Allyl-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-acetamide
CID 650451
N-tert-butyl-2-(4-hydroxy-4-phenylpiperidin-1-yl)acetamide
CID 649927
N-Allyl-2-[4-(4-fluoro-phenyl)-4-hydroxy-piperidin-1-yl]-acetamide
CID 653579
2-[4-Hydroxy-4-(3-trifluoromethyl-phenyl)-piperidin-1-yl]-N-phenethyl-acetamide
CID 3228837
2-(4-benzylpiperazin-1-yl)-N-[(2-hydroxyphenyl)methyl]acetamide
CID 25118358
2-(4-benzylpiperazin-1-yl)-N-[2-(2-hydroxyphenyl)ethyl]acetamide
CID 25118359
N-(3-Hydroxy-1,3,3-triphenylpropyl)ethanimidic acid
CID 26746

Frequently Asked Questions

What is the IUPAC name of 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide?
The IUPAC name of 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide (CID 646544) is 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide.
What is the SMILES notation for 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide?
The canonical SMILES for 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide is O=C(CN1CCC(O)(c2ccc(F)cc2)CC1)NCc1ccc(F)cc1.
What is the InChIKey of 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide?
The InChIKey is IUGWRZPTBAZRQI-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H22F2N2O2/c21-17-5-1-15(2-6-17)13-23-19(25)14-24-11-9-20(26,10-12-24)16-3-7-18(22)8-4-16/h1-8,26H,9-14H2,(H,23,25).
What are the key properties of 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide?
2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide has a molecular weight of 360.40 g/mol, XLogP of 2.56, 5 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]-N-[(4-fluorophenyl)methyl]acetamide is sourced from PubChem (CID 646544), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).