5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine

C14H18N6O — CID 66318979

IUPAC5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine
SMILESCOc1cc(N2CCN(c3ccc(N)nc3)CC2)ncn1
InChIInChI=1S/C14H18N6O/c1-21-14-8-13(17-10-18-14)20-6-4-19(5-7-20)11-2-3-12(15)16-9-11/h2-3,8-10H,4-7H2,1H3,(H2,15,16)
InChIKeyYYTHMOSEPXJXMS-UHFFFAOYSA-N
MW286.34 g/mol
LogP0.79
Rot. Bonds3

About 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine

5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine (PubChem CID 66318979) has the molecular formula C14H18N6O and a molecular weight of 286.34 g/mol. Its IUPAC name is 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine.

Molecular Properties

Compound Name5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine
PubChem CID66318979
Molecular FormulaC14H18N6O
Molecular Weight286.34 g/mol
Exact Mass286.15
IUPAC Name5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine
SMILESCOc1cc(N2CCN(c3ccc(N)nc3)CC2)ncn1
InChIInChI=1S/C14H18N6O/c1-21-14-8-13(17-10-18-14)20-6-4-19(5-7-20)11-2-3-12(15)16-9-11/h2-3,8-10H,4-7H2,1H3,(H2,15,16)
InChIKeyYYTHMOSEPXJXMS-UHFFFAOYSA-N
XLogP0.79
TPSA80.40 Ų
H-Bond Donors1
H-Bond Acceptors7
Rotatable Bonds3
Heavy Atoms21
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500286.34
LogP ≤ 50.79
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 107

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Related Compounds

5-[4-(5-chloro-2-pyridinyl)piperazin-1-yl]pyridin-2-amine
CID 60870212
5-[4-(2-methoxyethyl)piperazin-1-yl]pyridin-2-amine
CID 43461954
4-methoxy-6-(4-propan-2-ylpiperazin-1-yl)pyrimidine
CID 175647933
4-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridine-2-carbonitrile
CID 163345651
5-[4-(4-chlorophenyl)piperazin-1-yl]pyridin-2-amine
CID 43318150
5-(azepan-1-yl)pyridin-2-amine;dihydrochloride
CID 75537462
2-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]-6-methylpyrazine
CID 155799860
5-[4-(4-methoxyphenyl)piperazin-1-yl]pyrazin-2-amine
CID 80651957
5-(4-prop-1-en-2-ylpiperazin-1-yl)pyridin-2-amine
CID 176665681
2-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]-2-methylpropan-1-amine
CID 66318068
4-[4-(5-ethylpyrimidin-2-yl)piperazin-1-yl]-6-methoxypyrimidine
CID 146079556
6-(4-phenylpiperazin-1-yl)pyrimidin-4-amine
CID 78929760

Frequently Asked Questions

What is the IUPAC name of 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine?
The IUPAC name of 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine (CID 66318979) is 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine.
What is the SMILES notation for 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine?
The canonical SMILES for 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine is COc1cc(N2CCN(c3ccc(N)nc3)CC2)ncn1.
What is the InChIKey of 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine?
The InChIKey is YYTHMOSEPXJXMS-UHFFFAOYSA-N. The full InChI is InChI=1S/C14H18N6O/c1-21-14-8-13(17-10-18-14)20-6-4-19(5-7-20)11-2-3-12(15)16-9-11/h2-3,8-10H,4-7H2,1H3,(H2,15,16).
What are the key properties of 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine?
5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine has a molecular weight of 286.34 g/mol, XLogP of 0.79, 3 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[4-(6-methoxypyrimidin-4-yl)piperazin-1-yl]pyridin-2-amine is sourced from PubChem (CID 66318979), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).