About N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide
N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide (PubChem CID 66635256) has the molecular formula C28H30N4O
and a molecular weight of 438.58 g/mol. Its IUPAC name is N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide.
Molecular Properties
| Compound Name | N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide |
| PubChem CID | 66635256 |
| Molecular Formula | C28H30N4O |
| Molecular Weight | 438.58 g/mol |
| Exact Mass | 438.24 |
| IUPAC Name | N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide |
| SMILES | CC(=O)NC(C)Cc1ccc(C#Cc2ccnc(N3CCCC(c4ccccc4)C3)n2)cc1 |
| InChI | InChI=1S/C28H30N4O/c1-21(30-22(2)33)19-24-12-10-23(11-13-24)14-15-27-16-17-29-28(31-27)32-18-6-9-26(20-32)25-7-4-3-5-8-25/h3-5,7-8,10-13,16-17,21,26H,6,9,18-20H2,1-2H3,(H,30,33) |
| InChIKey | KZPQKNWHHYWPDF-UHFFFAOYSA-N |
| XLogP | 4.33 |
| TPSA | 58.12 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 438.58 |
| LogP ≤ 5 | 4.33 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'triple_bond', 'substructure': 'N/A'} |
|---|
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Frequently Asked Questions
What is the IUPAC name of N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide?
The IUPAC name of N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide (CID 66635256) is N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide.
What is the SMILES notation for N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide?
The canonical SMILES for N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide is CC(=O)NC(C)Cc1ccc(C#Cc2ccnc(N3CCCC(c4ccccc4)C3)n2)cc1.
What is the InChIKey of N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide?
The InChIKey is KZPQKNWHHYWPDF-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H30N4O/c1-21(30-22(2)33)19-24-12-10-23(11-13-24)14-15-27-16-17-29-28(31-27)32-18-6-9-26(20-32)25-7-4-3-5-8-25/h3-5,7-8,10-13,16-17,21,26H,6,9,18-20H2,1-2H3,(H,30,33).
What are the key properties of N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide?
N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide has a molecular weight of 438.58 g/mol, XLogP of 4.33, 5 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[1-[4-[2-[2-(3-phenylpiperidin-1-yl)pyrimidin-4-yl]ethynyl]phenyl]propan-2-yl]acetamide is sourced from PubChem (CID 66635256), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).