About 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide
4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide (PubChem CID 66779115) has the molecular formula C17H14ClF3N4OS
and a molecular weight of 414.84 g/mol. Its IUPAC name is 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide.
Molecular Properties
| Compound Name | 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide |
| PubChem CID | 66779115 |
| Molecular Formula | C17H14ClF3N4OS |
| Molecular Weight | 414.84 g/mol |
| Exact Mass | 414.05 |
| IUPAC Name | 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide |
| SMILES | CCCn1nc(C(F)(F)F)cc1-c1sc(C(N)=O)nc1-c1ccccc1Cl |
| InChI | InChI=1S/C17H14ClF3N4OS/c1-2-7-25-11(8-12(24-25)17(19,20)21)14-13(23-16(27-14)15(22)26)9-5-3-4-6-10(9)18/h3-6,8H,2,7H2,1H3,(H2,22,26) |
| InChIKey | PJXNBENSIDCCAY-UHFFFAOYSA-N |
| XLogP | 4.85 |
| TPSA | 73.80 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 27 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 414.84 |
| LogP ≤ 5 | 4.85 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide?
The IUPAC name of 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide (CID 66779115) is 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide.
What is the SMILES notation for 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide?
The canonical SMILES for 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide is CCCn1nc(C(F)(F)F)cc1-c1sc(C(N)=O)nc1-c1ccccc1Cl.
What is the InChIKey of 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide?
The InChIKey is PJXNBENSIDCCAY-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H14ClF3N4OS/c1-2-7-25-11(8-12(24-25)17(19,20)21)14-13(23-16(27-14)15(22)26)9-5-3-4-6-10(9)18/h3-6,8H,2,7H2,1H3,(H2,22,26).
What are the key properties of 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide?
4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide has a molecular weight of 414.84 g/mol, XLogP of 4.85, 5 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(2-chlorophenyl)-5-[1-propyl-3-(trifluoromethyl)pyrazol-5-yl]-1,3-thiazole-2-carboxamide is sourced from PubChem (CID 66779115), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).