About 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide
4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide (PubChem CID 66799652) has the molecular formula C20H16F3N3O4
and a molecular weight of 419.36 g/mol. Its IUPAC name is 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide.
Molecular Properties
| Compound Name | 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide |
| PubChem CID | 66799652 |
| Molecular Formula | C20H16F3N3O4 |
| Molecular Weight | 419.36 g/mol |
| Exact Mass | 419.11 |
| IUPAC Name | 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide |
| SMILES | NC(=O)c1cc([C@@H](O)CO)cc(-c2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)n1 |
| InChI | InChI=1S/C20H16F3N3O4/c21-20(22,23)13-3-6-18(25-9-13)30-14-4-1-11(2-5-14)15-7-12(17(28)10-27)8-16(26-15)19(24)29/h1-9,17,27-28H,10H2,(H2,24,29)/t17-/m0/s1 |
| InChIKey | OAYJPXIPEOHSKH-KRWDZBQOSA-N |
| XLogP | 3.08 |
| TPSA | 118.56 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 419.36 |
| LogP ≤ 5 | 3.08 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide?
The IUPAC name of 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide (CID 66799652) is 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide.
What is the SMILES notation for 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide?
The canonical SMILES for 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide is NC(=O)c1cc([C@@H](O)CO)cc(-c2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)n1.
What is the InChIKey of 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide?
The InChIKey is OAYJPXIPEOHSKH-KRWDZBQOSA-N. The full InChI is InChI=1S/C20H16F3N3O4/c21-20(22,23)13-3-6-18(25-9-13)30-14-4-1-11(2-5-14)15-7-12(17(28)10-27)8-16(26-15)19(24)29/h1-9,17,27-28H,10H2,(H2,24,29)/t17-/m0/s1.
What are the key properties of 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide?
4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide has a molecular weight of 419.36 g/mol, XLogP of 3.08, 6 rotatable bonds, 3 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[(1R)-1,2-dihydroxyethyl]-6-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyridine-2-carboxamide is sourced from PubChem (CID 66799652), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).