About [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone
[2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone (PubChem CID 67101929) has the molecular formula C24H26FN5O3
and a molecular weight of 451.50 g/mol. Its IUPAC name is [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone.
Molecular Properties
| Compound Name | [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone |
| PubChem CID | 67101929 |
| Molecular Formula | C24H26FN5O3 |
| Molecular Weight | 451.50 g/mol |
| Exact Mass | 451.20 |
| IUPAC Name | [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone |
| SMILES | O=C(c1cc(Nc2ncc3cccc(OC4CCNCC4)c3n2)ccc1F)N1CCOCC1 |
| InChI | InChI=1S/C24H26FN5O3/c25-20-5-4-17(14-19(20)23(31)30-10-12-32-13-11-30)28-24-27-15-16-2-1-3-21(22(16)29-24)33-18-6-8-26-9-7-18/h1-5,14-15,18,26H,6-13H2,(H,27,28,29) |
| InChIKey | SKYPZRLAILLFFA-UHFFFAOYSA-N |
| XLogP | 3.12 |
| TPSA | 88.61 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 451.50 |
| LogP ≤ 5 | 3.12 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone?
The IUPAC name of [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone (CID 67101929) is [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone.
What is the SMILES notation for [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone?
The canonical SMILES for [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone is O=C(c1cc(Nc2ncc3cccc(OC4CCNCC4)c3n2)ccc1F)N1CCOCC1.
What is the InChIKey of [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone?
The InChIKey is SKYPZRLAILLFFA-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H26FN5O3/c25-20-5-4-17(14-19(20)23(31)30-10-12-32-13-11-30)28-24-27-15-16-2-1-3-21(22(16)29-24)33-18-6-8-26-9-7-18/h1-5,14-15,18,26H,6-13H2,(H,27,28,29).
What are the key properties of [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone?
[2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone has a molecular weight of 451.50 g/mol, XLogP of 3.12, 5 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for [2-fluoro-5-[(8-piperidin-4-yloxyquinazolin-2-yl)amino]phenyl]-morpholin-4-ylmethanone is sourced from PubChem (CID 67101929), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).