About 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine
2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine (PubChem CID 68593598) has the molecular formula C22H25F3N6O
and a molecular weight of 446.48 g/mol. Its IUPAC name is 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine.
Molecular Properties
| Compound Name | 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine |
| PubChem CID | 68593598 |
| Molecular Formula | C22H25F3N6O |
| Molecular Weight | 446.48 g/mol |
| Exact Mass | 446.20 |
| IUPAC Name | 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine |
| SMILES | Cc1n[nH]c(C)c1C(C)N1CCN(c2nccnc2-c2ccc(OC(F)(F)F)cc2)CC1 |
| InChI | InChI=1S/C22H25F3N6O/c1-14-19(15(2)29-28-14)16(3)30-10-12-31(13-11-30)21-20(26-8-9-27-21)17-4-6-18(7-5-17)32-22(23,24)25/h4-9,16H,10-13H2,1-3H3,(H,28,29) |
| InChIKey | HTDFYMOVTUBRON-UHFFFAOYSA-N |
| XLogP | 4.27 |
| TPSA | 70.17 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 446.48 |
| LogP ≤ 5 | 4.27 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine?
The IUPAC name of 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine (CID 68593598) is 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine.
What is the SMILES notation for 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine?
The canonical SMILES for 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine is Cc1n[nH]c(C)c1C(C)N1CCN(c2nccnc2-c2ccc(OC(F)(F)F)cc2)CC1.
What is the InChIKey of 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine?
The InChIKey is HTDFYMOVTUBRON-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H25F3N6O/c1-14-19(15(2)29-28-14)16(3)30-10-12-31(13-11-30)21-20(26-8-9-27-21)17-4-6-18(7-5-17)32-22(23,24)25/h4-9,16H,10-13H2,1-3H3,(H,28,29).
What are the key properties of 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine?
2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine has a molecular weight of 446.48 g/mol, XLogP of 4.27, 5 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-[1-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl]piperazin-1-yl]-3-[4-(trifluoromethoxy)phenyl]pyrazine is sourced from PubChem (CID 68593598), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).