About (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine
(4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine (PubChem CID 68907799) has the molecular formula C26H29ClN2OS
and a molecular weight of 453.05 g/mol. Its IUPAC name is (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine.
Molecular Properties
| Compound Name | (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine |
| PubChem CID | 68907799 |
| Molecular Formula | C26H29ClN2OS |
| Molecular Weight | 453.05 g/mol |
| Exact Mass | 452.17 |
| IUPAC Name | (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine |
| SMILES | CCCC[C@H](C#CC(N)c1nc(-c2cc(C)c(OC)cc2Cl)c(C)s1)c1ccccc1 |
| InChI | InChI=1S/C26H29ClN2OS/c1-5-6-10-20(19-11-8-7-9-12-19)13-14-23(28)26-29-25(18(3)31-26)21-15-17(2)24(30-4)16-22(21)27/h7-9,11-12,15-16,20,23H,5-6,10,28H2,1-4H3/t20-,23?/m1/s1 |
| InChIKey | ADABYBYFKALNFB-PPUHSXQSSA-N |
| XLogP | 7.07 |
| TPSA | 48.14 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 453.05 |
| LogP ≤ 5 | 7.07 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'triple_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine?
The IUPAC name of (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine (CID 68907799) is (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine.
What is the SMILES notation for (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine?
The canonical SMILES for (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine is CCCC[C@H](C#CC(N)c1nc(-c2cc(C)c(OC)cc2Cl)c(C)s1)c1ccccc1.
What is the InChIKey of (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine?
The InChIKey is ADABYBYFKALNFB-PPUHSXQSSA-N. The full InChI is InChI=1S/C26H29ClN2OS/c1-5-6-10-20(19-11-8-7-9-12-19)13-14-23(28)26-29-25(18(3)31-26)21-15-17(2)24(30-4)16-22(21)27/h7-9,11-12,15-16,20,23H,5-6,10,28H2,1-4H3/t20-,23?/m1/s1.
What are the key properties of (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine?
(4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine has a molecular weight of 453.05 g/mol, XLogP of 7.07, 7 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for (4S)-1-[4-(2-chloro-4-methoxy-5-methylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-phenyloct-2-yn-1-amine is sourced from PubChem (CID 68907799), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).