About N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide
N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide (PubChem CID 69237694) has the molecular formula C23H35BrFN3O3SSi
and a molecular weight of 560.61 g/mol. Its IUPAC name is N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide.
Molecular Properties
| Compound Name | N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide |
| PubChem CID | 69237694 |
| Molecular Formula | C23H35BrFN3O3SSi |
| Molecular Weight | 560.61 g/mol |
| Exact Mass | 559.13 |
| IUPAC Name | N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide |
| SMILES | CC(C)(C)S(=O)(=O)N[C@@H](c1cn(COCC[Si](C)(C)C)nc1-c1cc(F)ccc1Br)C1CC1 |
| InChI | InChI=1S/C23H35BrFN3O3SSi/c1-23(2,3)32(29,30)27-21(16-7-8-16)19-14-28(15-31-11-12-33(4,5)6)26-22(19)18-13-17(25)9-10-20(18)24/h9-10,13-14,16,21,27H,7-8,11-12,15H2,1-6H3/t21-/m1/s1 |
| InChIKey | IOTQCKIXRCFGIA-OAQYLSRUSA-N |
| XLogP | 5.93 |
| TPSA | 73.22 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 10 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 560.61 |
| LogP ≤ 5 | 5.93 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide?
The IUPAC name of N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide (CID 69237694) is N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide.
What is the SMILES notation for N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide?
The canonical SMILES for N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide is CC(C)(C)S(=O)(=O)N[C@@H](c1cn(COCC[Si](C)(C)C)nc1-c1cc(F)ccc1Br)C1CC1.
What is the InChIKey of N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide?
The InChIKey is IOTQCKIXRCFGIA-OAQYLSRUSA-N. The full InChI is InChI=1S/C23H35BrFN3O3SSi/c1-23(2,3)32(29,30)27-21(16-7-8-16)19-14-28(15-31-11-12-33(4,5)6)26-22(19)18-13-17(25)9-10-20(18)24/h9-10,13-14,16,21,27H,7-8,11-12,15H2,1-6H3/t21-/m1/s1.
What are the key properties of N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide?
N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide has a molecular weight of 560.61 g/mol, XLogP of 5.93, 10 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(R)-[3-(2-bromo-5-fluorophenyl)-1-(2-trimethylsilylethoxymethyl)pyrazol-4-yl]-cyclopropylmethyl]-2-methylpropane-2-sulfonamide is sourced from PubChem (CID 69237694), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).