About N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide
N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide (PubChem CID 69451107) has the molecular formula C29H33F3N6O3
and a molecular weight of 570.62 g/mol. Its IUPAC name is N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide.
Molecular Properties
| Compound Name | N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide |
| PubChem CID | 69451107 |
| Molecular Formula | C29H33F3N6O3 |
| Molecular Weight | 570.62 g/mol |
| Exact Mass | 570.26 |
| IUPAC Name | N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide |
| SMILES | COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCN(C(=O)Nc3ccc(N(C)C)cc3C(F)(F)F)CC2)cc1 |
| InChI | InChI=1S/C29H33F3N6O3/c1-19-5-12-26(41-4)25(17-19)34-27(39)33-20-6-8-21(9-7-20)37-13-15-38(16-14-37)28(40)35-24-11-10-22(36(2)3)18-23(24)29(30,31)32/h5-12,17-18H,13-16H2,1-4H3,(H,35,40)(H2,33,34,39) |
| InChIKey | BKPRHDACQTUVDU-UHFFFAOYSA-N |
| XLogP | 6.09 |
| TPSA | 89.18 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 41 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 570.62 |
| LogP ≤ 5 | 6.09 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide?
The IUPAC name of N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide (CID 69451107) is N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide.
What is the SMILES notation for N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide?
The canonical SMILES for N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide is COc1ccc(C)cc1NC(=O)Nc1ccc(N2CCN(C(=O)Nc3ccc(N(C)C)cc3C(F)(F)F)CC2)cc1.
What is the InChIKey of N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide?
The InChIKey is BKPRHDACQTUVDU-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H33F3N6O3/c1-19-5-12-26(41-4)25(17-19)34-27(39)33-20-6-8-21(9-7-20)37-13-15-38(16-14-37)28(40)35-24-11-10-22(36(2)3)18-23(24)29(30,31)32/h5-12,17-18H,13-16H2,1-4H3,(H,35,40)(H2,33,34,39).
What are the key properties of N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide?
N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide has a molecular weight of 570.62 g/mol, XLogP of 6.09, 6 rotatable bonds, 3 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-[4-(dimethylamino)-2-(trifluoromethyl)phenyl]-4-[4-[(2-methoxy-5-methylphenyl)carbamoylamino]phenyl]piperazine-1-carboxamide is sourced from PubChem (CID 69451107), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).