1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone

C32H42N4O3S — CID 70687712

IUPAC1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone
SMILESC[C@]12Cc3cnn(C4CCCCC4)c3C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CSc1ncccn1
InChIInChI=1S/C32H42N4O3S/c1-30-16-20-18-35-36(22-7-4-3-5-8-22)25(20)15-21(30)9-10-23-24-11-12-32(39,31(24,2)17-26(37)28(23)30)27(38)19-40-29-33-13-6-14-34-29/h6,13-15,18,22-24,26,28,37,39H,3-5,7-12,16-17,19H2,1-2H3/t23-,24-,26-,28+,30-,31-,32-/m0/s1
InChIKeyNRQBSPLXYQJLHB-RQXSESNRSA-N
MW562.78 g/mol
LogP5.42
Rot. Bonds5

About 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone

1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone (PubChem CID 70687712) has the molecular formula C32H42N4O3S and a molecular weight of 562.78 g/mol. Its IUPAC name is 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone.

Molecular Properties

Compound Name1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone
PubChem CID70687712
Molecular FormulaC32H42N4O3S
Molecular Weight562.78 g/mol
Exact Mass562.30
IUPAC Name1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone
SMILESC[C@]12Cc3cnn(C4CCCCC4)c3C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CSc1ncccn1
InChIInChI=1S/C32H42N4O3S/c1-30-16-20-18-35-36(22-7-4-3-5-8-22)25(20)15-21(30)9-10-23-24-11-12-32(39,31(24,2)17-26(37)28(23)30)27(38)19-40-29-33-13-6-14-34-29/h6,13-15,18,22-24,26,28,37,39H,3-5,7-12,16-17,19H2,1-2H3/t23-,24-,26-,28+,30-,31-,32-/m0/s1
InChIKeyNRQBSPLXYQJLHB-RQXSESNRSA-N
XLogP5.42
TPSA101.13 Ų
H-Bond Donors2
H-Bond Acceptors8
Rotatable Bonds5
Heavy Atoms40
Complexity—

Lipinski Rule of Five

2 violations

RuleValue
MW ≤ 500562.78
LogP ≤ 55.42
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 108

Analyze 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone with MolForge

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Frequently Asked Questions

What is the IUPAC name of 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone?
The IUPAC name of 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone (CID 70687712) is 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone.
What is the SMILES notation for 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone?
The canonical SMILES for 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone is C[C@]12Cc3cnn(C4CCCCC4)c3C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CSc1ncccn1.
What is the InChIKey of 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone?
The InChIKey is NRQBSPLXYQJLHB-RQXSESNRSA-N. The full InChI is InChI=1S/C32H42N4O3S/c1-30-16-20-18-35-36(22-7-4-3-5-8-22)25(20)15-21(30)9-10-23-24-11-12-32(39,31(24,2)17-26(37)28(23)30)27(38)19-40-29-33-13-6-14-34-29/h6,13-15,18,22-24,26,28,37,39H,3-5,7-12,16-17,19H2,1-2H3/t23-,24-,26-,28+,30-,31-,32-/m0/s1.
What are the key properties of 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone?
1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone has a molecular weight of 562.78 g/mol, XLogP of 5.42, 5 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[(1S,2R,13S,14S,17R,18S,20S)-7-cyclohexyl-17,20-dihydroxy-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-yl]-2-pyrimidin-2-ylsulfanylethanone is sourced from PubChem (CID 70687712), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).