About 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane
1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane (PubChem CID 70782874) has the molecular formula C22H28F3N5
and a molecular weight of 419.50 g/mol. Its IUPAC name is 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane.
Molecular Properties
| Compound Name | 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane |
| PubChem CID | 70782874 |
| Molecular Formula | C22H28F3N5 |
| Molecular Weight | 419.50 g/mol |
| Exact Mass | 419.23 |
| IUPAC Name | 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane |
| SMILES | Cn1ncc(CN2CCCC23CCN(c2ccc(C(F)(F)F)cn2)CC3)c1C1CC1 |
| InChI | InChI=1S/C22H28F3N5/c1-28-20(16-3-4-16)17(13-27-28)15-30-10-2-7-21(30)8-11-29(12-9-21)19-6-5-18(14-26-19)22(23,24)25/h5-6,13-14,16H,2-4,7-12,15H2,1H3 |
| InChIKey | ZROIHKLYSGUYEE-UHFFFAOYSA-N |
| XLogP | 4.35 |
| TPSA | 37.19 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 419.50 |
| LogP ≤ 5 | 4.35 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane?
The IUPAC name of 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane (CID 70782874) is 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane.
What is the SMILES notation for 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane?
The canonical SMILES for 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane is Cn1ncc(CN2CCCC23CCN(c2ccc(C(F)(F)F)cn2)CC3)c1C1CC1.
What is the InChIKey of 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane?
The InChIKey is ZROIHKLYSGUYEE-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H28F3N5/c1-28-20(16-3-4-16)17(13-27-28)15-30-10-2-7-21(30)8-11-29(12-9-21)19-6-5-18(14-26-19)22(23,24)25/h5-6,13-14,16H,2-4,7-12,15H2,1H3.
What are the key properties of 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane?
1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane has a molecular weight of 419.50 g/mol, XLogP of 4.35, 4 rotatable bonds, 0 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[(5-cyclopropyl-1-methylpyrazol-4-yl)methyl]-8-[5-(trifluoromethyl)-2-pyridinyl]-1,8-diazaspiro[4.5]decane is sourced from PubChem (CID 70782874), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).