N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide

C20H17ClN4O2 — CID 70978019

IUPACN-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide
SMILESCc1ccncc1C(=O)Nc1cnc(-c2cc(OC3CC3)ccc2Cl)cn1
InChIInChI=1S/C20H17ClN4O2/c1-12-6-7-22-9-16(12)20(26)25-19-11-23-18(10-24-19)15-8-14(4-5-17(15)21)27-13-2-3-13/h4-11,13H,2-3H2,1H3,(H,24,25,26)
InChIKeyFAVCYJHGNOQIBK-UHFFFAOYSA-N
MW380.84 g/mol
LogP4.29
Rot. Bonds5

About N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide

N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide (PubChem CID 70978019) has the molecular formula C20H17ClN4O2 and a molecular weight of 380.84 g/mol. Its IUPAC name is N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide.

Molecular Properties

Compound NameN-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide
PubChem CID70978019
Molecular FormulaC20H17ClN4O2
Molecular Weight380.84 g/mol
Exact Mass380.10
IUPAC NameN-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide
SMILESCc1ccncc1C(=O)Nc1cnc(-c2cc(OC3CC3)ccc2Cl)cn1
InChIInChI=1S/C20H17ClN4O2/c1-12-6-7-22-9-16(12)20(26)25-19-11-23-18(10-24-19)15-8-14(4-5-17(15)21)27-13-2-3-13/h4-11,13H,2-3H2,1H3,(H,24,25,26)
InChIKeyFAVCYJHGNOQIBK-UHFFFAOYSA-N
XLogP4.29
TPSA77.00 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds5
Heavy Atoms27
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500380.84
LogP ≤ 54.29
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

Analyze N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[5-[2-chloro-5-[[6-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 71010141
N-[5-(2-ethyl-5-methoxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 126722767
N-[5-(2-chloro-5-propan-2-yloxyphenyl)-2-pyridinyl]-4-methylpyridine-3-carboxamide
CID 71010092
dipotassium;3-(5-aminopyrazin-2-yl)-4-chlorophenol;bromocyclopropane;5-bromopyrazin-2-amine;5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-amine;N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide;(2-chloro-5-hydroxyphenyl)boronic acid;dichloropalladium;hydride;methane;(4-methyl-3-pyridinyl) formate;oxido formate;tetrakis(triphenylphosphane)
CID 157066107
N-[5-[2-chloro-5-(trifluoromethyl)phenyl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;3-methylpyridine-4-carbonyl chloride
CID 160860559
N-[5-[5-[(3Z)-4-aminooxypenta-1,3-dien-2-yl]oxy-2-ethylphenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 89184659
N-[5-[5-[(3-fluoro-2-pyridinyl)oxy]-2-(trifluoromethoxy)phenyl]pyrazin-2-yl]-4-methylpyridine-3-carboxamide
CID 71010107
[4-chloro-3-[5-[2-(4-methyl-3-pyridinyl)-2-oxoethyl]pyrazin-2-yl]phenyl] methanesulfonate
CID 148789105
4-methyl-N-[5-[2-methyl-5-(2-methyl-1,3-thiazol-4-yl)phenyl]pyrazin-2-yl]pyridine-3-carboxamide
CID 70979582
N-[5-(6-chloro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-5-fluoro-2-methylbenzamide
CID 118343572
2-[5-[2-chloro-5-[(3-fluoro-2-pyridinyl)oxy]phenyl]pyrazin-2-yl]-1-(4-methyl-3-pyridinyl)ethanone
CID 149184392
N-(5-bromo-4-methyl-2-pyridinyl)-4-chloropyridine-3-carboxamide
CID 81232858

Frequently Asked Questions

What is the IUPAC name of N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide?
The IUPAC name of N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide (CID 70978019) is N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide.
What is the SMILES notation for N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide?
The canonical SMILES for N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide is Cc1ccncc1C(=O)Nc1cnc(-c2cc(OC3CC3)ccc2Cl)cn1.
What is the InChIKey of N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide?
The InChIKey is FAVCYJHGNOQIBK-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H17ClN4O2/c1-12-6-7-22-9-16(12)20(26)25-19-11-23-18(10-24-19)15-8-14(4-5-17(15)21)27-13-2-3-13/h4-11,13H,2-3H2,1H3,(H,24,25,26).
What are the key properties of N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide?
N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide has a molecular weight of 380.84 g/mol, XLogP of 4.29, 5 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-(2-chloro-5-cyclopropyloxyphenyl)pyrazin-2-yl]-4-methylpyridine-3-carboxamide is sourced from PubChem (CID 70978019), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).