7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine

C25H14F4N4 — CID 71180451

IUPAC7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine
SMILESFc1ccc(Nc2nc(-c3cccnc3)nc3cc(-c4cccc(F)c4F)ccc23)cc1F
InChIInChI=1S/C25H14F4N4/c26-19-9-7-16(12-21(19)28)31-25-18-8-6-14(17-4-1-5-20(27)23(17)29)11-22(18)32-24(33-25)15-3-2-10-30-13-15/h1-13H,(H,31,32,33)
InChIKeyQOZNXZCKEBJHGX-UHFFFAOYSA-N
MW446.41 g/mol
LogP6.66
Rot. Bonds4

About 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine

7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine (PubChem CID 71180451) has the molecular formula C25H14F4N4 and a molecular weight of 446.41 g/mol. Its IUPAC name is 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine.

Molecular Properties

Compound Name7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine
PubChem CID71180451
Molecular FormulaC25H14F4N4
Molecular Weight446.41 g/mol
Exact Mass446.12
IUPAC Name7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine
SMILESFc1ccc(Nc2nc(-c3cccnc3)nc3cc(-c4cccc(F)c4F)ccc23)cc1F
InChIInChI=1S/C25H14F4N4/c26-19-9-7-16(12-21(19)28)31-25-18-8-6-14(17-4-1-5-20(27)23(17)29)11-22(18)32-24(33-25)15-3-2-10-30-13-15/h1-13H,(H,31,32,33)
InChIKeyQOZNXZCKEBJHGX-UHFFFAOYSA-N
XLogP6.66
TPSA50.70 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms33
Complexity—

Lipinski Rule of Five

1 violation

RuleValue
MW ≤ 500446.41
LogP ≤ 56.66
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

Analyze 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-[4-(3,4-difluoroanilino)-2-pyridin-3-ylquinazolin-6-yl]benzonitrile
CID 71180181
8-chloro-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine
CID 71180050
N-(3,4-difluorophenyl)-8-methyl-2-pyridin-3-ylquinazolin-4-amine
CID 71180072
7-bromo-N-(4-fluoro-3-methylphenyl)-2-pyridin-3-ylquinazolin-4-amine
CID 144501523
3-[[7-(4-fluorophenyl)-2-pyridin-3-ylquinazolin-4-yl]amino]benzonitrile
CID 71274262
7-chloro-N-(3-ethynyl-4-fluorophenyl)-2-pyridin-3-ylquinazolin-4-amine
CID 144500888
4-(3-chloro-4-fluoroanilino)-N-methyl-2-pyridin-3-ylquinazoline-7-carboxamide
CID 71180244
4-N-(3-chloro-4-fluorophenyl)-7-N-(oxan-4-yl)-2-pyridin-3-ylquinazoline-4,7-diamine
CID 71180955
7-chloro-N-(1H-indazol-5-yl)-2-pyridin-3-ylquinazolin-4-amine
CID 10292688
6-(3,4-difluorophenyl)-N,7-dimethyl-2-pyridin-3-ylquinazolin-4-amine
CID 71180161
3-[4-(3-chloro-4-fluoroanilino)-2-pyridin-3-ylquinazolin-7-yl]propan-1-ol
CID 71181124
7-fluoro-6-(3-fluorophenyl)-N-methyl-2-pyridin-3-ylquinazolin-4-amine
CID 71151562

Frequently Asked Questions

What is the IUPAC name of 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine?
The IUPAC name of 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine (CID 71180451) is 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine.
What is the SMILES notation for 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine?
The canonical SMILES for 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine is Fc1ccc(Nc2nc(-c3cccnc3)nc3cc(-c4cccc(F)c4F)ccc23)cc1F.
What is the InChIKey of 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine?
The InChIKey is QOZNXZCKEBJHGX-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H14F4N4/c26-19-9-7-16(12-21(19)28)31-25-18-8-6-14(17-4-1-5-20(27)23(17)29)11-22(18)32-24(33-25)15-3-2-10-30-13-15/h1-13H,(H,31,32,33).
What are the key properties of 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine?
7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine has a molecular weight of 446.41 g/mol, XLogP of 6.66, 4 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 7-(2,3-difluorophenyl)-N-(3,4-difluorophenyl)-2-pyridin-3-ylquinazolin-4-amine is sourced from PubChem (CID 71180451), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).