4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one

C18H15N3O2S2 — CID 71292583

IUPAC4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one
SMILESCC1=C(c2nc(-c3cccs3)cs2)C(c2cccc(O)c2)NC(=O)N1
InChIInChI=1S/C18H15N3O2S2/c1-10-15(17-20-13(9-25-17)14-6-3-7-24-14)16(21-18(23)19-10)11-4-2-5-12(22)8-11/h2-9,16,22H,1H3,(H2,19,21,23)
InChIKeyUEEGQSOVQGFTHG-UHFFFAOYSA-N
MW369.47 g/mol
LogP4.36
Rot. Bonds3

About 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one

4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one (PubChem CID 71292583) has the molecular formula C18H15N3O2S2 and a molecular weight of 369.47 g/mol. Its IUPAC name is 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one.

Molecular Properties

Compound Name4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one
PubChem CID71292583
Molecular FormulaC18H15N3O2S2
Molecular Weight369.47 g/mol
Exact Mass369.06
IUPAC Name4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one
SMILESCC1=C(c2nc(-c3cccs3)cs2)C(c2cccc(O)c2)NC(=O)N1
InChIInChI=1S/C18H15N3O2S2/c1-10-15(17-20-13(9-25-17)14-6-3-7-24-14)16(21-18(23)19-10)11-4-2-5-12(22)8-11/h2-9,16,22H,1H3,(H2,19,21,23)
InChIKeyUEEGQSOVQGFTHG-UHFFFAOYSA-N
XLogP4.36
TPSA74.25 Ų
H-Bond Donors3
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500369.47
LogP ≤ 54.36
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 105

Analyze 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

4-[4-(3-Hydroxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine
CID 10472893
4-[2-[4-(4-hydroxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidin-5-yl]thiazol-4-yl]benzonitrile
CID 71292658
4-[2-[4-(3-hydroxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidin-5-yl]thiazol-4-yl]benzonitrile
CID 71608044
4-[2-[(4R)-4-(3-hydroxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidin-5-yl]-1,3-thiazol-4-yl]benzonitrile
CID 137659362
3-[2-[4-(3-hydroxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidin-5-yl]thiazol-4-yl]benzonitrile
CID 71292521
5-[4-(4-chlorophenyl)thiazol-2-yl]-4-(3-hydroxyphenyl)-6-methyl-3,4-dihydro-1H-pyrimidin-2-one
CID 71292523
4-[2-[6-(3-Hydroxyphenyl)-3,4-dimethyl-2-oxo-1,6-dihydropyrimidin-5-yl]thiazol-4-yl]benzonitrile
CID 71292524
4-(3-hydroxyphenyl)-6-methyl-5-[4-[4-(trifluoromethyl)phenyl]thiazol-2-yl]-3,4-dihydro-1H-pyrimidin-2-one
CID 71292525
5-[4-(4-bromophenyl)thiazol-2-yl]-4-(3-hydroxyphenyl)-6-methyl-3,4-dihydro-1H-pyrimidin-2-one
CID 71292561
5-[4-(4-fluorophenyl)thiazol-2-yl]-4-(3-hydroxyphenyl)-6-methyl-3,4-dihydro-1H-pyrimidin-2-one
CID 71292595
3-[2-[4-(4-hydroxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidin-5-yl]thiazol-4-yl]benzonitrile
CID 71505546
N-[(3-methoxyphenyl)-(4-thiophen-2-yl-1,3-thiazol-2-yl)methyl]acetamide
CID 49778500

Frequently Asked Questions

What is the IUPAC name of 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one?
The IUPAC name of 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one (CID 71292583) is 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one.
What is the SMILES notation for 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one?
The canonical SMILES for 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one is CC1=C(c2nc(-c3cccs3)cs2)C(c2cccc(O)c2)NC(=O)N1.
What is the InChIKey of 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one?
The InChIKey is UEEGQSOVQGFTHG-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H15N3O2S2/c1-10-15(17-20-13(9-25-17)14-6-3-7-24-14)16(21-18(23)19-10)11-4-2-5-12(22)8-11/h2-9,16,22H,1H3,(H2,19,21,23).
What are the key properties of 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one?
4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one has a molecular weight of 369.47 g/mol, XLogP of 4.36, 3 rotatable bonds, 3 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(3-hydroxyphenyl)-6-methyl-5-(4-thiophen-2-yl-1,3-thiazol-2-yl)-3,4-dihydro-1H-pyrimidin-2-one is sourced from PubChem (CID 71292583), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).