About 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide
5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide (PubChem CID 71452037) has the molecular formula C20H21BrFN5O
and a molecular weight of 446.32 g/mol. Its IUPAC name is 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide.
Molecular Properties
| Compound Name | 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide |
| PubChem CID | 71452037 |
| Molecular Formula | C20H21BrFN5O |
| Molecular Weight | 446.32 g/mol |
| Exact Mass | 445.09 |
| IUPAC Name | 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide |
| SMILES | CNCCCNc1c(C(=O)NCc2ccc(F)cc2)nc(Br)c2cccnc12 |
| InChI | InChI=1S/C20H21BrFN5O/c1-23-9-3-11-25-17-16-15(4-2-10-24-16)19(21)27-18(17)20(28)26-12-13-5-7-14(22)8-6-13/h2,4-8,10,23,25H,3,9,11-12H2,1H3,(H,26,28) |
| InChIKey | ZZZJDPAUPRELIQ-UHFFFAOYSA-N |
| XLogP | 3.48 |
| TPSA | 78.94 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 446.32 |
| LogP ≤ 5 | 3.48 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide?
The IUPAC name of 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide (CID 71452037) is 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide.
What is the SMILES notation for 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide?
The canonical SMILES for 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide is CNCCCNc1c(C(=O)NCc2ccc(F)cc2)nc(Br)c2cccnc12.
What is the InChIKey of 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide?
The InChIKey is ZZZJDPAUPRELIQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H21BrFN5O/c1-23-9-3-11-25-17-16-15(4-2-10-24-16)19(21)27-18(17)20(28)26-12-13-5-7-14(22)8-6-13/h2,4-8,10,23,25H,3,9,11-12H2,1H3,(H,26,28).
What are the key properties of 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide?
5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide has a molecular weight of 446.32 g/mol, XLogP of 3.48, 8 rotatable bonds, 3 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 5-bromo-N-[(4-fluorophenyl)methyl]-8-[3-(methylamino)propylamino]-1,6-naphthyridine-7-carboxamide is sourced from PubChem (CID 71452037), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).