About 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid
3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid (PubChem CID 71734672) has the molecular formula C24H11Cl2F3O5
and a molecular weight of 507.25 g/mol. Its IUPAC name is 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid.
Molecular Properties
| Compound Name | 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid |
| PubChem CID | 71734672 |
| Molecular Formula | C24H11Cl2F3O5 |
| Molecular Weight | 507.25 g/mol |
| Exact Mass | 505.99 |
| IUPAC Name | 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid |
| SMILES | O=C(O)c1cc2c(C#Cc3ccc(Cl)c(Cl)c3)c(-c3ccc(OC(F)(F)F)cc3)oc2cc1O |
| InChI | InChI=1S/C24H11Cl2F3O5/c25-18-8-2-12(9-19(18)26)1-7-15-16-10-17(23(31)32)20(30)11-21(16)33-22(15)13-3-5-14(6-4-13)34-24(27,28)29/h2-6,8-11,30H,(H,31,32) |
| InChIKey | HRJZQYKXWXVHCF-UHFFFAOYSA-N |
| XLogP | 7.11 |
| TPSA | 79.90 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 34 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 507.25 |
| LogP ≤ 5 | 7.11 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'triple_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid?
The IUPAC name of 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid (CID 71734672) is 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid.
What is the SMILES notation for 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid?
The canonical SMILES for 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid is O=C(O)c1cc2c(C#Cc3ccc(Cl)c(Cl)c3)c(-c3ccc(OC(F)(F)F)cc3)oc2cc1O.
What is the InChIKey of 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid?
The InChIKey is HRJZQYKXWXVHCF-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H11Cl2F3O5/c25-18-8-2-12(9-19(18)26)1-7-15-16-10-17(23(31)32)20(30)11-21(16)33-22(15)13-3-5-14(6-4-13)34-24(27,28)29/h2-6,8-11,30H,(H,31,32).
What are the key properties of 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid?
3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid has a molecular weight of 507.25 g/mol, XLogP of 7.11, 3 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[2-(3,4-dichlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acid is sourced from PubChem (CID 71734672), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).