About N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide
N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide (PubChem CID 776634) has the molecular formula C18H20FN3OS
and a molecular weight of 345.44 g/mol. Its IUPAC name is N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide.
Molecular Properties
| Compound Name | N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide |
| PubChem CID | 776634 |
| Molecular Formula | C18H20FN3OS |
| Molecular Weight | 345.44 g/mol |
| Exact Mass | 345.13 |
| IUPAC Name | N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide |
| SMILES | COc1ccccc1N1CCN(C(=S)Nc2ccc(F)cc2)CC1 |
| InChI | InChI=1S/C18H20FN3OS/c1-23-17-5-3-2-4-16(17)21-10-12-22(13-11-21)18(24)20-15-8-6-14(19)7-9-15/h2-9H,10-13H2,1H3,(H,20,24) |
| InChIKey | JCPIWTOZSRDACY-UHFFFAOYSA-N |
| XLogP | 3.35 |
| TPSA | 27.74 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 24 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 345.44 |
| LogP ≤ 5 | 3.35 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 3 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'} |
|---|
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Frequently Asked Questions
What is the IUPAC name of N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide?
The IUPAC name of N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide (CID 776634) is N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide.
What is the SMILES notation for N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide?
The canonical SMILES for N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide is COc1ccccc1N1CCN(C(=S)Nc2ccc(F)cc2)CC1.
What is the InChIKey of N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide?
The InChIKey is JCPIWTOZSRDACY-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H20FN3OS/c1-23-17-5-3-2-4-16(17)21-10-12-22(13-11-21)18(24)20-15-8-6-14(19)7-9-15/h2-9H,10-13H2,1H3,(H,20,24).
What are the key properties of N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide?
N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide has a molecular weight of 345.44 g/mol, XLogP of 3.35, 3 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for N-(4-fluorophenyl)-4-(2-methoxyphenyl)piperazine-1-carbothioamide is sourced from PubChem (CID 776634), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).