About 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine
6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine (PubChem CID 80972687) has the molecular formula C12H17ClF3N3O
and a molecular weight of 311.74 g/mol. Its IUPAC name is 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine.
Molecular Properties
| Compound Name | 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine |
| PubChem CID | 80972687 |
| Molecular Formula | C12H17ClF3N3O |
| Molecular Weight | 311.74 g/mol |
| Exact Mass | 311.10 |
| IUPAC Name | 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine |
| SMILES | Cc1c(Cl)nc(C(C)C)nc1NCCOCC(F)(F)F |
| InChI | InChI=1S/C12H17ClF3N3O/c1-7(2)10-18-9(13)8(3)11(19-10)17-4-5-20-6-12(14,15)16/h7H,4-6H2,1-3H3,(H,17,18,19) |
| InChIKey | SPVZGILNEFGKPG-UHFFFAOYSA-N |
| XLogP | 3.55 |
| TPSA | 47.04 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 20 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 311.74 |
| LogP ≤ 5 | 3.55 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine?
The IUPAC name of 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine (CID 80972687) is 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine.
What is the SMILES notation for 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine?
The canonical SMILES for 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine is Cc1c(Cl)nc(C(C)C)nc1NCCOCC(F)(F)F.
What is the InChIKey of 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine?
The InChIKey is SPVZGILNEFGKPG-UHFFFAOYSA-N. The full InChI is InChI=1S/C12H17ClF3N3O/c1-7(2)10-18-9(13)8(3)11(19-10)17-4-5-20-6-12(14,15)16/h7H,4-6H2,1-3H3,(H,17,18,19).
What are the key properties of 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine?
6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine has a molecular weight of 311.74 g/mol, XLogP of 3.55, 6 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 6-chloro-5-methyl-2-propan-2-yl-N-[2-(2,2,2-trifluoroethoxy)ethyl]pyrimidin-4-amine is sourced from PubChem (CID 80972687), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).