About 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide
1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide (PubChem CID 86687377) has the molecular formula C20H12BrF3N4O2S
and a molecular weight of 509.31 g/mol. Its IUPAC name is 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide.
Molecular Properties
| Compound Name | 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide |
| PubChem CID | 86687377 |
| Molecular Formula | C20H12BrF3N4O2S |
| Molecular Weight | 509.31 g/mol |
| Exact Mass | 507.98 |
| IUPAC Name | 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide |
| SMILES | O=S(=O)(Nc1ccncn1)c1ccc2c(-c3ccc(C(F)(F)F)cc3Br)nccc2c1 |
| InChI | InChI=1S/C20H12BrF3N4O2S/c21-17-10-13(20(22,23)24)1-3-16(17)19-15-4-2-14(9-12(15)5-8-26-19)31(29,30)28-18-6-7-25-11-27-18/h1-11H,(H,25,27,28) |
| InChIKey | HRELXNQPVKVZFI-UHFFFAOYSA-N |
| XLogP | 5.27 |
| TPSA | 84.84 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 509.31 |
| LogP ≤ 5 | 5.27 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide?
The IUPAC name of 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide (CID 86687377) is 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide.
What is the SMILES notation for 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide?
The canonical SMILES for 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide is O=S(=O)(Nc1ccncn1)c1ccc2c(-c3ccc(C(F)(F)F)cc3Br)nccc2c1.
What is the InChIKey of 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide?
The InChIKey is HRELXNQPVKVZFI-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H12BrF3N4O2S/c21-17-10-13(20(22,23)24)1-3-16(17)19-15-4-2-14(9-12(15)5-8-26-19)31(29,30)28-18-6-7-25-11-27-18/h1-11H,(H,25,27,28).
What are the key properties of 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide?
1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide has a molecular weight of 509.31 g/mol, XLogP of 5.27, 4 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[2-bromo-4-(trifluoromethyl)phenyl]-N-pyrimidin-4-ylisoquinoline-6-sulfonamide is sourced from PubChem (CID 86687377), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).