8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide

C27H24F5N5O2 — CID 86724784

About 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide

8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide (PubChem CID 86724784) has the molecular formula C27H24F5N5O2 and a molecular weight of 545.51 g/mol. Its IUPAC name is 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide
• PubChem CID: 86724784
• Molecular Formula: C27H24F5N5O2
• Molecular Weight: 545.51 g/mol
• Exact Mass: 545.19
• IUPAC Name: 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide
• SMILES: Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NC3CC(C)Nc4ccc(C(F)(F)F)nc43)n2c1
• InChI: InChI=1S/C27H24F5N5O2/c1-13-9-21(39-12-16-17(28)5-4-6-18(16)29)25-34-15(3)24(37(25)11-13)26(38)35-20-10-14(2)33-19-7-8-22(27(30,31)32)36-23(19)20/h4-9,11,14,20,33H,10,12H2,1-3H3,(H,35,38)
• InChIKey: JVXXIWCVXBVCET-UHFFFAOYSA-N
• XLogP: 5.90
• TPSA: 80.55 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 6
• Rotatable Bonds: 5
• Heavy Atoms: 39
• Complexity: —

Lipinski Rule of Five

2 violations

Rule	Value
MW ≤ 500	545.51
LogP ≤ 5	5.90
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	6

Frequently Asked Questions

What is the IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide?

The IUPAC name of 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide (CID 86724784) is 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide.

What is the SMILES notation for 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide?

The canonical SMILES for 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide is Cc1cc(OCc2c(F)cccc2F)c2nc(C)c(C(=O)NC3CC(C)Nc4ccc(C(F)(F)F)nc43)n2c1.

What is the InChIKey of 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide?

The InChIKey is JVXXIWCVXBVCET-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H24F5N5O2/c1-13-9-21(39-12-16-17(28)5-4-6-18(16)29)25-34-15(3)24(37(25)11-13)26(38)35-20-10-14(2)33-19-7-8-22(27(30,31)32)36-23(19)20/h4-9,11,14,20,33H,10,12H2,1-3H3,(H,35,38).

What are the key properties of 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide?

8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide has a molecular weight of 545.51 g/mol, XLogP of 5.90, 5 rotatable bonds, 2 hydrogen bond donors, and 6 hydrogen bond acceptors.

Where does this data come from?

All data for 8-[(2,6-difluorophenyl)methoxy]-2,6-dimethyl-N-[2-methyl-6-(trifluoromethyl)-1,2,3,4-tetrahydro-1,5-naphthyridin-4-yl]imidazo[1,2-a]pyridine-3-carboxamide is sourced from PubChem (CID 86724784), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).