About 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide
2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide (PubChem CID 86764594) has the molecular formula C23H30FN5O2
and a molecular weight of 427.52 g/mol. Its IUPAC name is 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide.
Molecular Properties
| Compound Name | 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide |
| PubChem CID | 86764594 |
| Molecular Formula | C23H30FN5O2 |
| Molecular Weight | 427.52 g/mol |
| Exact Mass | 427.24 |
| IUPAC Name | 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide |
| SMILES | CC(C(=O)NC1CC1C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C)ncc3F)C2)cc1 |
| InChI | InChI=1S/C23H30FN5O2/c1-14-11-20(14)26-22(30)15(2)16-5-7-17(8-6-16)31-18-9-10-29(13-18)21-19(24)12-25-23(27-21)28(3)4/h5-8,12,14-15,18,20H,9-11,13H2,1-4H3,(H,26,30)/t14?,15?,18-,20?/m1/s1 |
| InChIKey | GXKYUGCEZDXWKO-IEMWXTKNSA-N |
| XLogP | 2.97 |
| TPSA | 70.59 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 427.52 |
| LogP ≤ 5 | 2.97 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide?
The IUPAC name of 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide (CID 86764594) is 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide.
What is the SMILES notation for 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide?
The canonical SMILES for 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide is CC(C(=O)NC1CC1C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C)ncc3F)C2)cc1.
What is the InChIKey of 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide?
The InChIKey is GXKYUGCEZDXWKO-IEMWXTKNSA-N. The full InChI is InChI=1S/C23H30FN5O2/c1-14-11-20(14)26-22(30)15(2)16-5-7-17(8-6-16)31-18-9-10-29(13-18)21-19(24)12-25-23(27-21)28(3)4/h5-8,12,14-15,18,20H,9-11,13H2,1-4H3,(H,26,30)/t14?,15?,18-,20?/m1/s1.
What are the key properties of 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide?
2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide has a molecular weight of 427.52 g/mol, XLogP of 2.97, 7 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-[(3R)-1-[2-(dimethylamino)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N-(2-methylcyclopropyl)propanamide is sourced from PubChem (CID 86764594), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).