[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone

C66H49Cl3F9N15O6 — CID 87577988

About [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone

[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone (PubChem CID 87577988) has the molecular formula C66H49Cl3F9N15O6 and a molecular weight of 1425.56 g/mol. Its IUPAC name is [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone.

Molecular Properties

• Compound Name: [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone
• PubChem CID: 87577988
• Molecular Formula: C66H49Cl3F9N15O6
• Molecular Weight: 1425.56 g/mol
• Exact Mass: 1423.29
• IUPAC Name: [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone
• SMILES: Cc1[nH]ncc1C1=CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)CC1.O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)C1CC(c2cncnc2)=CCN1.O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)N1CC=C(C2=CNC=NC2)CC1
• InChI: InChI=1S/2C22H17ClF3N5O2.C22H15ClF3N5O2/c1-12-16(9-27-29-12)13-2-5-30(6-3-13)21(32)18-19(23)31-10-15(14-4-7-33-11-14)8-17(20(31)28-18)22(24,25)26;23-19-18(21(32)30-4-1-13(2-5-30)16-8-27-12-28-9-16)29-20-17(22(24,25)26)7-15(10-31(19)20)14-3-6-33-11-14;23-20-18(19(32)17-6-12(1-3-29-17)15-7-27-11-28-8-15)30-21-16(22(24,25)26)5-14(9-31(20)21)13-2-4-33-10-13/h2,4,7-11H,3,5-6H2,1H3,(H,27,29);1,3,6-8,10-12H,2,4-5,9H2,(H,27,28);1-2,4-5,7-11,17,29H,3,6H2
• InChIKey: IYRUCZGSDCXJKK-UHFFFAOYSA-N
• XLogP: 14.47
• TPSA: 239.89 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 18
• Rotatable Bonds: 10
• Heavy Atoms: 99
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1425.56
LogP ≤ 5	14.47
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	18

Frequently Asked Questions

What is the IUPAC name of [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone?

The IUPAC name of [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone (CID 87577988) is [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone.

What is the SMILES notation for [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone?

The canonical SMILES for [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone is Cc1[nH]ncc1C1=CCN(C(=O)c2nc3c(C(F)(F)F)cc(-c4ccoc4)cn3c2Cl)CC1.O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)C1CC(c2cncnc2)=CCN1.O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)N1CC=C(C2=CNC=NC2)CC1.

What is the InChIKey of [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone?

The InChIKey is IYRUCZGSDCXJKK-UHFFFAOYSA-N. The full InChI is InChI=1S/2C22H17ClF3N5O2.C22H15ClF3N5O2/c1-12-16(9-27-29-12)13-2-5-30(6-3-13)21(32)18-19(23)31-10-15(14-4-7-33-11-14)8-17(20(31)28-18)22(24,25)26;23-19-18(21(32)30-4-1-13(2-5-30)16-8-27-12-28-9-16)29-20-17(22(24,25)26)7-15(10-31(19)20)14-3-6-33-11-14;23-20-18(19(32)17-6-12(1-3-29-17)15-7-27-11-28-8-15)30-21-16(22(24,25)26)5-14(9-31(20)21)13-2-4-33-10-13/h2,4,7-11H,3,5-6H2,1H3,(H,27,29);1,3,6-8,10-12H,2,4-5,9H2,(H,27,28);1-2,4-5,7-11,17,29H,3,6H2.

What are the key properties of [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone?

[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone has a molecular weight of 1425.56 g/mol, XLogP of 14.47, 10 rotatable bonds, 3 hydrogen bond donors, and 18 hydrogen bond acceptors.

Where does this data come from?

All data for [3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(1,4-dihydropyrimidin-5-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-[4-(5-methyl-1H-pyrazol-4-yl)-3,6-dihydro-2H-pyridin-1-yl]methanone;[3-chloro-6-(furan-3-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-(4-pyrimidin-5-yl-1,2,3,6-tetrahydropyridin-2-yl)methanone is sourced from PubChem (CID 87577988), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).