About (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one
(5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one (PubChem CID 89091102) has the molecular formula C19H25F3IN2O2P
and a molecular weight of 528.29 g/mol. Its IUPAC name is (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one.
Molecular Properties
| Compound Name | (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one |
| PubChem CID | 89091102 |
| Molecular Formula | C19H25F3IN2O2P |
| Molecular Weight | 528.29 g/mol |
| Exact Mass | 528.07 |
| IUPAC Name | (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one |
| SMILES | C=C[C@](P)(CO[C@H](C)c1cc(C)cc(C(F)(F)F)c1)NC[C@]1(I)CCC(=O)N1 |
| InChI | InChI=1S/C19H25F3IN2O2P/c1-4-18(28,24-10-17(23)6-5-16(26)25-17)11-27-13(3)14-7-12(2)8-15(9-14)19(20,21)22/h4,7-9,13,24H,1,5-6,10-11,28H2,2-3H3,(H,25,26)/t13-,17+,18+/m1/s1 |
| InChIKey | KWLFPDRTXHEBBX-BVGQSLNGSA-N |
| XLogP | 4.48 |
| TPSA | 50.36 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 3 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 528.29 |
| LogP ≤ 5 | 4.48 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 3 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'alkyl_halide', 'substructure': 'N/A'}, {'alert_name': 'iodine', 'substructure': 'N/A'}, {'alert_name': 'isolated_alkene', 'substructure': 'N/A'}, {'alert_name': 'N-C-halo', 'substructure': 'N/A'}, {'alert_name': 'phosphor', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one?
The IUPAC name of (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one (CID 89091102) is (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one.
What is the SMILES notation for (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one?
The canonical SMILES for (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one is C=C[C@](P)(CO[C@H](C)c1cc(C)cc(C(F)(F)F)c1)NC[C@]1(I)CCC(=O)N1.
What is the InChIKey of (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one?
The InChIKey is KWLFPDRTXHEBBX-BVGQSLNGSA-N. The full InChI is InChI=1S/C19H25F3IN2O2P/c1-4-18(28,24-10-17(23)6-5-16(26)25-17)11-27-13(3)14-7-12(2)8-15(9-14)19(20,21)22/h4,7-9,13,24H,1,5-6,10-11,28H2,2-3H3,(H,25,26)/t13-,17+,18+/m1/s1.
What are the key properties of (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one?
(5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one has a molecular weight of 528.29 g/mol, XLogP of 4.48, 8 rotatable bonds, 2 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for (5R)-5-iodo-5-[[[(2S)-1-[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]-2-phosphanylbut-3-en-2-yl]amino]methyl]pyrrolidin-2-one is sourced from PubChem (CID 89091102), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).