4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile

C27H30F4N8 — CID 89442851

About 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile

4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile (PubChem CID 89442851) has the molecular formula C27H30F4N8 and a molecular weight of 542.59 g/mol. Its IUPAC name is 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile.

Molecular Properties

• Compound Name: 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile
• PubChem CID: 89442851
• Molecular Formula: C27H30F4N8
• Molecular Weight: 542.59 g/mol
• Exact Mass: 542.25
• IUPAC Name: 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile
• SMILES: N#Cc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCNC2CCCC2)CC1
• InChI: InChI=1S/C27H30F4N8/c28-22-6-5-18(13-21(22)27(29,30)31)23-15-39(12-9-34-19-3-1-2-4-19)25(37-23)17-7-10-38(11-8-17)26-20(14-32)24(33)35-16-36-26/h5-6,13,15-17,19,34H,1-4,7-12H2,(H2,33,35,36)
• InChIKey: CDOPSCORKPCGMU-UHFFFAOYSA-N
• XLogP: 4.87
• TPSA: 108.68 Ų
• H-Bond Donors: 2
• H-Bond Acceptors: 8
• Rotatable Bonds: 7
• Heavy Atoms: 39
• Complexity: —

Lipinski Rule of Five

1 violation

Rule	Value
MW ≤ 500	542.59
LogP ≤ 5	4.87
H-Bond Donors ≤ 5	2
H-Bond Acceptors ≤ 10	8

Frequently Asked Questions

What is the IUPAC name of 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile?

The IUPAC name of 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile (CID 89442851) is 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile.

What is the SMILES notation for 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile?

The canonical SMILES for 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile is N#Cc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCNC2CCCC2)CC1.

What is the InChIKey of 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile?

The InChIKey is CDOPSCORKPCGMU-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H30F4N8/c28-22-6-5-18(13-21(22)27(29,30)31)23-15-39(12-9-34-19-3-1-2-4-19)25(37-23)17-7-10-38(11-8-17)26-20(14-32)24(33)35-16-36-26/h5-6,13,15-17,19,34H,1-4,7-12H2,(H2,33,35,36).

What are the key properties of 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile?

4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile has a molecular weight of 542.59 g/mol, XLogP of 4.87, 7 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.

Where does this data come from?

All data for 4-amino-6-[4-[1-[2-(cyclopentylamino)ethyl]-4-[4-fluoro-3-(trifluoromethyl)phenyl]imidazol-2-yl]piperidin-1-yl]pyrimidine-5-carbonitrile is sourced from PubChem (CID 89442851), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).