N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide

C22H21F3N6O2 — CID 90331282

IUPACN-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide
SMILESC=CC(=O)Nc1cc(C)ccc1Nc1nc(Nc2cc(C)nc(OC)c2)ncc1C(F)(F)F
InChIInChI=1S/C22H21F3N6O2/c1-5-18(32)29-17-8-12(2)6-7-16(17)30-20-15(22(23,24)25)11-26-21(31-20)28-14-9-13(3)27-19(10-14)33-4/h5-11H,1H2,2-4H3,(H,29,32)(H2,26,27,28,30,31)
InChIKeyUXNFZZOPVKCTTK-UHFFFAOYSA-N
MW458.44 g/mol
LogP5.13
Rot. Bonds7

About N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide

N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide (PubChem CID 90331282) has the molecular formula C22H21F3N6O2 and a molecular weight of 458.44 g/mol. Its IUPAC name is N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide.

Molecular Properties

Compound NameN-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide
PubChem CID90331282
Molecular FormulaC22H21F3N6O2
Molecular Weight458.44 g/mol
Exact Mass458.17
IUPAC NameN-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide
SMILESC=CC(=O)Nc1cc(C)ccc1Nc1nc(Nc2cc(C)nc(OC)c2)ncc1C(F)(F)F
InChIInChI=1S/C22H21F3N6O2/c1-5-18(32)29-17-8-12(2)6-7-16(17)30-20-15(22(23,24)25)11-26-21(31-20)28-14-9-13(3)27-19(10-14)33-4/h5-11H,1H2,2-4H3,(H,29,32)(H2,26,27,28,30,31)
InChIKeyUXNFZZOPVKCTTK-UHFFFAOYSA-N
XLogP5.13
TPSA101.06 Ų
H-Bond Donors3
H-Bond Acceptors7
Rotatable Bonds7
Heavy Atoms33
Complexity—

Lipinski Rule of Five

1 violation

RuleValue
MW ≤ 500458.44
LogP ≤ 55.13
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 107

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}

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Frequently Asked Questions

What is the IUPAC name of N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide?
The IUPAC name of N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide (CID 90331282) is N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide.
What is the SMILES notation for N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide?
The canonical SMILES for N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide is C=CC(=O)Nc1cc(C)ccc1Nc1nc(Nc2cc(C)nc(OC)c2)ncc1C(F)(F)F.
What is the InChIKey of N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide?
The InChIKey is UXNFZZOPVKCTTK-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H21F3N6O2/c1-5-18(32)29-17-8-12(2)6-7-16(17)30-20-15(22(23,24)25)11-26-21(31-20)28-14-9-13(3)27-19(10-14)33-4/h5-11H,1H2,2-4H3,(H,29,32)(H2,26,27,28,30,31).
What are the key properties of N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide?
N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide has a molecular weight of 458.44 g/mol, XLogP of 5.13, 7 rotatable bonds, 3 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for N-[2-[[2-[(2-methoxy-6-methyl-4-pyridinyl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]-5-methylphenyl]prop-2-enamide is sourced from PubChem (CID 90331282), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).