About [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol
[1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol (PubChem CID 90445939) has the molecular formula C23H22F2N6O2
and a molecular weight of 452.50 g/mol. Its IUPAC name is [1-[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol.
Molecular Properties
| Compound Name | [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol |
| PubChem CID | 90445939 |
| Molecular Formula | C23H22F2N6O2 |
| Molecular Weight | 452.50 g/mol |
| Exact Mass | 452.18 |
| IUPAC Name | [1-[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol |
| SMILES | C1CCN(C(C1)CO)C2=NC(=NC=C2F)C3=NN(C(=C3)C4=NOC=C4)CC5=CC=CC=C5F |
| InChI | InChI=1S/C23H22F2N6O2/c24-17-7-2-1-5-15(17)13-31-21(19-8-10-33-29-19)11-20(28-31)22-26-12-18(25)23(27-22)30-9-4-3-6-16(30)14-32/h1-2,5,7-8,10-12,16,32H,3-4,6,9,13-14H2 |
| InChIKey | BKVQAHJOGKEOBG-UHFFFAOYSA-N |
| XLogP | 2.80 |
| TPSA | 93.10 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 9 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 33 |
| Complexity | 636 |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 452.50 |
| LogP ≤ 5 | 2.80 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 9 |
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Frequently Asked Questions
What is the IUPAC name of [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol?
The IUPAC name of [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol (CID 90445939) is [1-[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol.
What is the SMILES notation for [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol?
The canonical SMILES for [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol is C1CCN(C(C1)CO)C2=NC(=NC=C2F)C3=NN(C(=C3)C4=NOC=C4)CC5=CC=CC=C5F.
What is the InChIKey of [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol?
The InChIKey is BKVQAHJOGKEOBG-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H22F2N6O2/c24-17-7-2-1-5-15(17)13-31-21(19-8-10-33-29-19)11-20(28-31)22-26-12-18(25)23(27-22)30-9-4-3-6-16(30)14-32/h1-2,5,7-8,10-12,16,32H,3-4,6,9,13-14H2.
What are the key properties of [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol?
[1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol has a molecular weight of 452.50 g/mol, XLogP of 2.80, 6 rotatable bonds, 1 hydrogen bond donors, and 9 hydrogen bond acceptors.
Where does this data come from?
All data for [1-[5-Fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]piperidin-2-yl]methanol is sourced from PubChem (CID 90445939), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).