About 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide
3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide (PubChem CID 91050349) has the molecular formula C22H19F3N6O2
and a molecular weight of 456.43 g/mol. Its IUPAC name is 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide.
Molecular Properties
| Compound Name | 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide |
| PubChem CID | 91050349 |
| Molecular Formula | C22H19F3N6O2 |
| Molecular Weight | 456.43 g/mol |
| Exact Mass | 456.15 |
| IUPAC Name | 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide |
| SMILES | Cc1ccc(C(N)=O)cc1Nc1ncc(C(F)(F)F)c(NCc2cccc3c[nH]c(O)c23)n1 |
| InChI | InChI=1S/C22H19F3N6O2/c1-11-5-6-12(18(26)32)7-16(11)30-21-29-10-15(22(23,24)25)19(31-21)27-8-13-3-2-4-14-9-28-20(33)17(13)14/h2-7,9-10,28,33H,8H2,1H3,(H2,26,32)(H2,27,29,30,31) |
| InChIKey | CWQHYYQKKHHKQJ-UHFFFAOYSA-N |
| XLogP | 4.45 |
| TPSA | 128.95 Ų |
| H-Bond Donors | 5 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 456.43 |
| LogP ≤ 5 | 4.45 |
| H-Bond Donors ≤ 5 | 5 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide?
The IUPAC name of 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide (CID 91050349) is 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide.
What is the SMILES notation for 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide?
The canonical SMILES for 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide is Cc1ccc(C(N)=O)cc1Nc1ncc(C(F)(F)F)c(NCc2cccc3c[nH]c(O)c23)n1.
What is the InChIKey of 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide?
The InChIKey is CWQHYYQKKHHKQJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H19F3N6O2/c1-11-5-6-12(18(26)32)7-16(11)30-21-29-10-15(22(23,24)25)19(31-21)27-8-13-3-2-4-14-9-28-20(33)17(13)14/h2-7,9-10,28,33H,8H2,1H3,(H2,26,32)(H2,27,29,30,31).
What are the key properties of 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide?
3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide has a molecular weight of 456.43 g/mol, XLogP of 4.45, 6 rotatable bonds, 5 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[[4-[(3-hydroxy-2H-isoindol-4-yl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-4-methylbenzamide is sourced from PubChem (CID 91050349), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).