About 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol
2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol (PubChem CID 91328159) has the molecular formula C22H18ClF4N5O2
and a molecular weight of 495.86 g/mol. Its IUPAC name is 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol.
Molecular Properties
| Compound Name | 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol |
| PubChem CID | 91328159 |
| Molecular Formula | C22H18ClF4N5O2 |
| Molecular Weight | 495.86 g/mol |
| Exact Mass | 495.11 |
| IUPAC Name | 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol |
| SMILES | Oc1c(C/N=N/c2ncc(F)c(N3CCOCC3)n2)ccc(-c2cccc(C(F)(F)F)c2)c1Cl |
| InChI | InChI=1S/C22H18ClF4N5O2/c23-18-16(13-2-1-3-15(10-13)22(25,26)27)5-4-14(19(18)33)11-29-31-21-28-12-17(24)20(30-21)32-6-8-34-9-7-32/h1-5,10,12,33H,6-9,11H2/b31-29+ |
| InChIKey | FATUIEGRYTVPPQ-OWWNRXNESA-N |
| XLogP | 5.78 |
| TPSA | 83.20 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 34 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 495.86 |
| LogP ≤ 5 | 5.78 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 7 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'azo_A(324)', 'substructure': 'N/A'}, {'alert_name': 'mannich_A(296)', 'substructure': 'N/A'}, {'alert_name': 'diazo_group', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol?
The IUPAC name of 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol (CID 91328159) is 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol.
What is the SMILES notation for 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol?
The canonical SMILES for 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol is Oc1c(C/N=N/c2ncc(F)c(N3CCOCC3)n2)ccc(-c2cccc(C(F)(F)F)c2)c1Cl.
What is the InChIKey of 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol?
The InChIKey is FATUIEGRYTVPPQ-OWWNRXNESA-N. The full InChI is InChI=1S/C22H18ClF4N5O2/c23-18-16(13-2-1-3-15(10-13)22(25,26)27)5-4-14(19(18)33)11-29-31-21-28-12-17(24)20(30-21)32-6-8-34-9-7-32/h1-5,10,12,33H,6-9,11H2/b31-29+.
What are the key properties of 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol?
2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol has a molecular weight of 495.86 g/mol, XLogP of 5.78, 5 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 2-chloro-6-[[(5-fluoro-4-morpholin-4-ylpyrimidin-2-yl)diazenyl]methyl]-3-[3-(trifluoromethyl)phenyl]phenol is sourced from PubChem (CID 91328159), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).