T cell receptor delta variable 2 (TRDV2)

About T cell receptor delta variable 2

T cell receptor delta variable 2 (TRDV2) is a protein from Homo sapiens identified by UniProt accession A0JD36, 115 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	T cell receptor delta variable 2
UniProt accession	A0JD36
Gene	TRDV2
Organism	Homo sapiens
Length	115 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

acute myeloid leukemia · score 0.03
cancer · score 0.01
Thymoma · score 0.01
chronic kidney disease · score 0.01
COVID-19 · score 0.00
autoimmune thrombocytopenic purpura · score 0.00
renal cell carcinoma · score 0.00
papillary thyroid carcinoma · score 0.00
toxoplasmosis · score 0.00
brucellosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A0JD36-F1	alphafold	PREDICTED	89.93	—

Amino-acid sequence (115 residues)

MQRISSLIHL SLFWAGVMSA IELVPEHQTV PVSIGVPATL RCSMKGEAIG NYYINWYRKT QGNTMTFIYR EKDIYGPGFK DNFQGDIDIA KNLAVLKILA PSERDEGSYY CACDT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards