Protein FAM170A (FAM170A)

About Protein FAM170A

Protein FAM170A (FAM170A) is a protein from Homo sapiens identified by UniProt accession A1A519, 330 residues long. MolForge cross-references it against 0 known binders and 121 disease associations.

Target properties

Protein name	Protein FAM170A
UniProt accession	A1A519
Gene	FAM170A
Organism	Homo sapiens
Length	330 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (121)

Diseases linked to this target (Open Targets).

body mass index · score 0.22
FEV/FVC ratio · score 0.19
drug use measurement · score 0.15
body height · score 0.15
azoospermia · score 0.09
male infertility with teratozoospermia due to single gene mutation · score 0.08
partial chromosome Y deletion · score 0.07
spermatogenic failure 65 · score 0.07
spermatogenic failure 56 · score 0.07
spermatogenic failure, X-linked, 3 · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1A519-F1	alphafold	PREDICTED	56.67	—

Amino-acid sequence (330 residues)

MKRRQKRKHL ENEESQETAE KGGGMSKSQE DALQPGSTRV AKGWSQGVGE VTSTSEYCSC VSSSRKLIHS GIQRIHRDSP QPQSPLAQVQ ERGETPPRSQ HVSLSSYSSY KTCVSSLCVN KEERGMKIYY MQVQMNKGVA VSWETEETLE SLEKQPRMEE VTLSEVVRVG TPPSDVSTRN LLSDSEPSGE EKEHEERTES DSLPGSPTVE DTPRAKTPDW LVTMENGFRC MACCRVFTTM EALQEHVQFG IREGFSCHVF HLTMAQLTGN MESESTQDEQ EEENGNEKEE EEKPEAKEEE GQPTEEDLGL RRSWSQCPGC VFHSPKDRNS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards