Keratin-associated protein 23-1 (KRTAP23-1)

About Keratin-associated protein 23-1

Keratin-associated protein 23-1 (KRTAP23-1) is a protein from Homo sapiens identified by UniProt accession A1A580, 65 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Keratin-associated protein 23-1
UniProt accession	A1A580
Gene	KRTAP23-1
Organism	Homo sapiens
Length	65 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.18
esophageal cancer · score 0.14
antisocial behaviour measurement · score 0.02
attention deficit hyperactivity disorder · score 0.02
substance abuse · score 0.02
smoking status measurement · score 0.02
gastric carcinoma · score 0.01
diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1A580-F1	alphafold	PREDICTED	57.33	—

Amino-acid sequence (65 residues)

MSYNCCCGNF SSHSCEGYLC YSGYSRGGSS YPSNLVYSTE PLISQHLPAG FLSLQGLSGD LLGNP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards