RNA-binding protein MEX3A (MEX3A)

About RNA-binding protein MEX3A

RNA-binding protein MEX3A (MEX3A) is a protein from Homo sapiens identified by UniProt accession A1L020, 520 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.

Target properties

Protein name	RNA-binding protein MEX3A
UniProt accession	A1L020
Gene	MEX3A
Organism	Homo sapiens
Length	520 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (95)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.56
body mass index · score 0.31
waist circumference · score 0.20
body height · score 0.20
lean body mass · score 0.15
systolic blood pressure · score 0.15
lysosomal storage disease · score 0.15
fat body mass · score 0.13
neoplasm · score 0.10
urate measurement · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1L020-F1	alphafold	PREDICTED	64.69	—

Amino-acid sequence (520 residues)

MPSLVVSGIM ERNGGFGELG CFGGSAKDRG LLEDERALQL ALDQLCLLGL GEPPAPTAGE DGGGGGGGAP AQPAAPPQPA PPPPPAAPPA APTAAPAAQT PQPPTAPKGA SDAKLCALYK EAELRLKGSS NTTECVPVPT SEHVAEIVGR QGCKIKALRA KTNTYIKTPV RGEEPVFMVT GRREDVATAR REIISAAEHF SMIRASRNKS GAAFGVAPAL PGQVTIRVRV PYRVVGLVVG PKGATIKRIQ QQTNTYIITP SRDRDPVFEI TGAPGNVERA REEIETHIAV RTGKILEYNN ENDFLAGSPD AAIDSRYSDA WRVHQPGCKP LSTFRQNSLG CIGECGVDSG FEAPRLGEQG GDFGYGGYLF PGYGVGKQDV YYGVAETSPP LWAGQENATP TSVLFSSASS SSSSSAKARA GPPGAHRSPA TSAGPELAGL PRRPPGEPLQ GFSKLGGGGL RSPGGGRDCM VCFESEVTAA LVPCGHNLFC MECAVRICER TDPECPVCHI TATQAIRIFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards