About Tetraspanin-11
Tetraspanin-11 (TSPAN11) is a protein
from Homo sapiens identified by UniProt accession
A1L157, 253 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Tetraspanin-11 |
|---|
| UniProt accession | A1L157 |
|---|
| Gene | TSPAN11 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 253 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- optic disc size measurement · score 0.29
- colorectal cancer · score 0.02
- neoplasm · score 0.02
- autism · score 0.02
- Ataxia-telangiectasia · score 0.02
- Down syndrome · score 0.01
- astrocytoma · score 0.01
- cancer · score 0.01
- oligodendroglioma · score 0.01
- head and neck squamous cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A1L157-F1 | alphafold | PREDICTED | 87.71 | — |
Amino-acid sequence (253 residues)
MAHYKTEQDD WLIIYLKYLL FVFNFFFWVG GAAVLAVGIW TLVEKSGYLS VLASSTFAAS AYILIFAGVL VMVTGFLGFG AILWERKGCL STYFCLLLVI FLVELVAGVL AHVYYQRLSD ELKQHLNRTL AENYGQPGAT QITASVDRLQ QDFKCCGSNS SADWQHSTYI LLREAEGRQV PDSCCKTVVV RCGQRAHPSN IYKVEGGCLT KLEQFLADHL LLMGAVGIGV ACLQICGMVL TCCLHQRLQR HFY
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