About Glutamate-rich protein 2
Glutamate-rich protein 2 (ERICH2) is a protein
from Homo sapiens identified by UniProt accession
A1L162, 156 residues long.
MolForge cross-references it against 0 known binders and
90 disease associations.
Target properties
| Protein name | Glutamate-rich protein 2 |
|---|
| UniProt accession | A1L162 |
|---|
| Gene | ERICH2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 156 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (90)
Diseases linked to this target (Open Targets).
- cognitive function measurement · score 0.25
- waist circumference · score 0.23
- mathematical ability · score 0.23
- triglyceride measurement · score 0.22
- sex hormone-binding globulin measurement · score 0.20
- body fat percentage · score 0.20
- metabolic syndrome · score 0.17
- type 2 diabetes mellitus · score 0.16
- serum alanine aminotransferase measurement · score 0.15
- aspartate aminotransferase measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A1L162-F1 | alphafold | PREDICTED | 73.63 | — |
Amino-acid sequence (156 residues)
METVNEPETG EVSKDAVIVK QEKNNEYCLQ DIDDKLSESA EDDGEDDTND EDDDEDSNPK KNTQAPLELM AEFLRAEMAR EYQLAKKLCQ MILIYEPENP EAKEFFTLIE EMLLMEKTQN HEQDGENSDE DSSGESKGES DEELSDESSD EGEDGS
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