Ubiquitin-conjugating enzyme E2Q-like protein 1…

About Ubiquitin-conjugating enzyme E2Q-like protein 1

Ubiquitin-conjugating enzyme E2Q-like protein 1 (UBE2QL1) is a protein from Homo sapiens identified by UniProt accession A1L167, 161 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Ubiquitin-conjugating enzyme E2Q-like protein 1
UniProt accession	A1L167
Gene	UBE2QL1
Organism	Homo sapiens
Length	161 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

renal cell carcinoma · score 0.08
atypical teratoid rhabdoid tumor · score 0.05
glioblastoma multiforme · score 0.04
von Willebrand factor measurement · score 0.03
ependymoma · score 0.03
Ataxia-telangiectasia · score 0.03
kidney neoplasm · score 0.03
large cell medulloblastoma · score 0.03
astrocytoma · score 0.03
oligodendroglioma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1L167-F1	alphafold	PREDICTED	90.97	—

Amino-acid sequence (161 residues)

MKELQDIARL SDRFISVELV DESLFDWNVK LHQVDKDSVL WQDMKETNTE FILLNLTFPD NFPFSPPFMR VLSPRLENGY VLDGGAICME LLTPRGWSSA YTVEAVMRQF AASLVKGQGR ICRKAGKSKK SFSRKEAEAT FKSLVKTHEK YGWVTPPVSD G

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Ubiquitin-conjugating enzyme E2Q-like protein 1 (UBE2QL1)