Uncharacterized protein C1orf226 (C1orf226)

About Uncharacterized protein C1orf226

Uncharacterized protein C1orf226 (C1orf226) is a protein from Homo sapiens identified by UniProt accession A1L170, 272 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	Uncharacterized protein C1orf226
UniProt accession	A1L170
Gene	C1orf226
Organism	Homo sapiens
Length	272 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (32)

Diseases linked to this target (Open Targets).

monocyte count · score 0.16
monocyte percentage of leukocytes · score 0.15
QT interval · score 0.13
electrocardiography · score 0.13
mean reticulocyte volume · score 0.12
granulocyte percentage of myeloid white cells · score 0.11
mean corpuscular volume · score 0.11
lymphocyte:monocyte ratio · score 0.07
blood protein measurement · score 0.07
longitudinal BMI measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1L170-F1	alphafold	PREDICTED	56.25	—

Amino-acid sequence (272 residues)

MFENLNTALT PKLQASRSFP HLSKPVAPGS APLGSGEPGG PGLWVGSSQH LKNLGKAMGA KVNDFLRRKE PSSLGSVGVT EINKTAGAQL ASGTDAAPEA WLEDERSVLQ ETFPRLDPPP PITRKRTPRA LKTTQDMLIS SQPVLSSLEY GTEPSPGQAQ DSAPTAQPDV PADASQPEAT MEREERGKVL PNGEVSLSVP DLIHKDSQDE SKLKMTECRR ASSPSLIERN GFKLSLSPIS LAESWEDGSP PPQARTSSLD NEGPHPDLLS FE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards