G antigen 12B/C/D/E (GAGE12B)

About G antigen 12B/C/D/E

G antigen 12B/C/D/E (GAGE12B) is a protein from Homo sapiens identified by UniProt accession A1L429, 117 residues long. MolForge cross-references it against 0 known binders and 1 disease associations.

Target properties

Protein name	G antigen 12B/C/D/E
UniProt accession	A1L429
Gene	GAGE12B
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1)

Diseases linked to this target (Open Targets).

genetic disorder · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A1L429-F1	alphafold	PREDICTED	63.17	—

Amino-acid sequence (117 residues)

MSWRGRSTYY WPRPRRYVQP PEMIGPMRPE QFSDEVEPAT PEEGEPATQC QDPAAAQEGE DEGASAGQGP KPEAHSQEQG HPQTGCECED GPDGQEMDPP NPEEVKTPEE GEKQSQC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards