About Serine protease 38
Serine protease 38 (PRSS38) is a protein
from Homo sapiens identified by UniProt accession
A1L453, 326 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Serine protease 38 |
|---|
| UniProt accession | A1L453 |
|---|
| Gene | PRSS38 |
|---|
| Organism | Homo sapiens |
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| Length | 326 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.19
- triglyceride measurement · score 0.15
- hematocrit · score 0.15
- hemoglobin measurement · score 0.05
- hair color · score 0.04
- breast carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A1L453-F1 | alphafold | PREDICTED | 81.10 | — |
Amino-acid sequence (326 residues)
MAAPASVMGP LGPSALGLLL LLLVVAPPRV AALVHRQPEN QGISLTGSVA CGRPSMEGKI LGGVPAPERK WPWQVSVHYA GLHVCGGSIL NEYWVLSAAH CFHRDKNIKI YDMYVGLVNL RVAGNHTQWY EVNRVILHPT YEMYHPIGGD VALVQLKTRI VFSESVLPVC LATPEVNLTS ANCWATGWGL VSKQGETSDE LQEMQLPLIL EPWCHLLYGH MSYIMPDMLC AGDILNAKTV CEGDSGGPLV CEFNRSWLQI GIVSWGRGCS NPLYPGVYAS VSYFSKWICD NIEITPTPAQ PAPALSPALG PTLSVLMAML AGWSVL
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